IRAK-4 Inhibitors for Inflammation

od Wang, Zhulun, Wesche, Holger, Stevens, Tracey, Walker, Nigel, Yeh, Wen-Chen
Izdano 2009

The structure of mitogen-activated protein kinase p38 at 2.1-Å resolution

od Wang, Zhulun, Harkins, Paul C., Ulevitch, Richard J., Han, Jiahuai, Cobb, Melanie H., Goldsmith, Elizabeth J.
Izdano 1997

Agonistic β-Klotho antibody mimics fibroblast growth factor 21 (FGF21) functions

od Min, Xiaoshan, Weiszmann, Jennifer, Johnstone, Sheree, Wang, Wei, Yu, Xinchao, Romanow, William, Thibault, Stephen, Li, Yang, Wang, Zhulun
izdano v J Biol Chem (2018)

Cryo-EM structure of ABCG5/G8 in complex with modulating antibodies

od Zhang, Hanzhi, Huang, Ching-Shin, Yu, Xinchao, Lee, Jonas, Vaish, Amit, Chen, Qing, Zhou, Mingyue, Wang, Zhulun, Min, Xiaoshan
izdano v Commun Biol (2021)

FGF19-induced Hepatocyte Proliferation Is Mediated through FGFR4 Activation

od Wu, Xinle, Ge, Hongfei, Lemon, Bryan, Vonderfecht, Steven, Weiszmann, Jennifer, Hecht, Randy, Gupte, Jamila, Hager, Todd, Wang, Zhulun, Lindberg, Richard, Li, Yang
Izdano 2010

Separating mitogenic and metabolic activities of fibroblast growth factor 19 (FGF19)

od Wu, Xinle, Ge, Hongfei, Lemon, Bryan, Vonderfecht, Steven, Baribault, Helene, Weiszmann, Jennifer, Gupte, Jamila, Gardner, Jonitha, Lindberg, Richard, Wang, Zhulun, Li, Yang
Izdano 2010

A systematic dissection of sequence elements determining β-Klotho and FGF interaction and signaling

od Shi, Sally Yu, Lu, Ya-Wen, Richardson, Jason, Min, Xiaoshan, Weiszmann, Jennifer, Richards, William G., Wang, Zhulun, Zhang, Zhongqi, Zhang, Jun, Li, Yang
izdano v Sci Rep (2018)

Cryo-EM structures of NPC1L1 reveal mechanisms of cholesterol transport and ezetimibe inhibition

od Huang, Ching-Shin, Yu, Xinchao, Fordstrom, Preston, Choi, Kaylee, Chung, Ben C., Roh, Soung-Hun, Chiu, Wah, Zhou, Mingyue, Min, Xiaoshan, Wang, Zhulun
izdano v Sci Adv (2020)

The serum protein transthyretin as a platform for dimerization and tetramerization of antibodies and Fab fragments to enable target clustering

od Walker, Kenneth W., Foltz, Ian N., Wang, Tina, Salimi-Moosavi, Hossein, Bailis, Julie M., Lee, Fei, An, Phillip, Smith, Stephen, Bruno, Richele, Wang, Zhulun
izdano v J Biol Chem (2020)

Rational selection of building blocks for the assembly of bispecific antibodies

od Gong, Danyang, Riley, Timothy P., Bzymek, Krzysztof P., Correia, Ana R., Li, Danqing, Spahr, Christopher, Robinson, John H., Case, Ryan B., Wang, Zhulun, Garces, Fernando
izdano v MAbs (2021)

Structure of the Nuclear Factor κB-inducing Kinase (NIK) Kinase Domain Reveals a Constitutively Active Conformation

od Liu, Jinsong, Sudom, Athena, Min, Xiaoshan, Cao, Zhaodan, Gao, Xiong, Ayres, Merrill, Lee, Fei, Cao, Ping, Johnstone, Sheree, Plotnikova, Olga, Walker, Nigel, Chen, Guoqing, Wang, Zhulun
Izdano 2012

Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2)

od Min, Xiaoshan, Ungureanu, Daniela, Maxwell, Sarah, Hammarén, Henrik, Thibault, Steve, Hillert, Ellin-Kristina, Ayres, Merrill, Greenfield, Brad, Eksterowicz, John, Gabel, Chris, Walker, Nigel, Silvennoinen, Olli, Wang, Zhulun
izdano v J Biol Chem (2015)

Enhancing the Prefusion Conformational Stability of SARS-CoV-2 Spike Protein Through Structure-Guided Design

od Riley, Timothy P., Chou, Hui-Ting, Hu, Ruozhen, Bzymek, Krzysztof P., Correia, Ana R., Partin, Alexander C., Li, Danqing, Gong, Danyang, Wang, Zhulun, Yu, Xinchao, Manzanillo, Paolo, Garces, Fernando
izdano v Front Immunol (2021)

Structure-guided Discovery of Dual-recognition Chemibodies

od Cheng, Alan C., Doherty, Elizabeth M., Johnstone, Sheree, DiMauro, Erin F., Dao, Jennifer, Luthra, Abhinav, Ye, Jay, Tang, Jie, Nixey, Thomas, Min, Xiaoshan, Tagari, Philip, Miranda, Les P., Wang, Zhulun
izdano v Sci Rep (2018)

Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH)

od Min, Xiaoshan, Thibault, Stephen T., Porter, Amy C., Gustin, Darin J., Carlson, Timothy J., Xu, Haoda, Lindstrom, Michelle, Xu, Guifen, Uyeda, Craig, Ma, Zhihua, Li, Yihong, Kayser, Frank, Walker, Nigel P. C., Wang, Zhulun
Izdano 2011

The high-resolution crystal structure of human LCAT(1)

od Piper, Derek E., Romanow, William G., Gunawardane, Ruwanthi N., Fordstrom, Preston, Masterman, Stephanie, Pan, Oscar, Thibault, Stephen T., Zhang, Richard, Meininger, David, Schwarz, Margrit, Wang, Zhulun, King, Chadwick, Zhou, Mingyue, Walker, Nigel P. C.
izdano v J Lipid Res (2015)

Identification and Characterization of a Non-retinoid Ligand for Retinol-binding Protein 4 Which Lowers Serum Retinol-binding Protein 4 Levels in Vivo

od Motani, Alykhan, Wang, Zhulun, Conn, Marion, Siegler, Karen, Zhang, Ying, Liu, Qingxiang, Johnstone, Sheree, Xu, Haoda, Thibault, Steve, Wang, Yingcai, Fan, Pingchen, Connors, Richard, Le, Hoa, Xu, Guifen, Walker, Nigel, Shan, Bei, Coward, Peter
Izdano 2009

Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor

od Min, Xiaoshan, Yie, Junming, Wang, Jinghong, Chung, Ben C., Huang, Ching-Shin, Xu, Haoda, Yang, Jie, Deng, Liying, Lin, Joanne, Chen, Qing, Abbott, Christina M., Gundel, Caroline, Thibault, Stephen A., Meng, Tina, Bates, Darren L., Lloyd, David J., Véniant, Murielle M., Wang, Zhulun
izdano v MAbs (2020)

An Inhibitory Antibody against Dipeptidyl Peptidase IV Improves Glucose Tolerance in Vivo

od Tang, Jie, Majeti, Jiangwen, Sudom, Athena, Xiong, Yumei, Lu, Mei, Liu, Qiang, Higbee, Jared, Zhang, Yi, Wang, Yan, Wang, Wei, Cao, Ping, Xia, Zhen, Johnstone, Sheree, Min, Xiaoshan, Yang, Xiaoping, Shao, Hui, Yu, Timothy, Sharkov, Nik, Walker, Nigel, Tu, Hua, Shen, Wenyan, Wang, Zhulun
Izdano 2013

Discovery of [1,2,4]Triazolo[1,5-a]pyridine Derivatives as Potent and Orally Bioavailable RORγt Inverse Agonists

od Nakajima, Ryota, Oono, Hiroyuki, Sugiyama, Sakae, Matsueda, Yohei, Ida, Tomohide, Kakuda, Shinji, Hirata, Jun, Baba, Atsushi, Makino, Akito, Matsuyama, Ryo, White, Ryan D., Wurz, Ryan Ρ., Shin, Youngsook, Min, Xiaoshan, Guzman-Perez, Angel, Wang, Zhulun, Symons, Antony, Singh, Sanjay K., Mothe, Srinivasa Reddy, Belyakov, Sergei, Chakrabarti, Anjan, Shuto, Satoshi
izdano v ACS Med Chem Lett (2020)