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FGF19-induced Hepatocyte Proliferation Is Mediated through FGFR4 Activation

FGF19 and FGF21, unique members of the fibroblast growth factor (FGF) family, are hormones that regulate glucose, lipid, and energy homeostasis. Increased hepatocyte proliferation and liver tumor formation have also been observed in FGF19 transgenic mice. Here, we report that, in contrast to FGF19,...

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Bibliografische gegevens
Hoofdauteurs: Wu, Xinle, Ge, Hongfei, Lemon, Bryan, Vonderfecht, Steven, Weiszmann, Jennifer, Hecht, Randy, Gupte, Jamila, Hager, Todd, Wang, Zhulun, Lindberg, Richard, Li, Yang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820743/
https://ncbi.nlm.nih.gov/pubmed/20018895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.068783
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