C-terminal Tail of FGF19 Determines Its Specificity toward Klotho Co-receptors

FGF19 subfamily proteins (FGF19, FGF21, and FGF23) are unique members of fibroblast growth factors (FGFs) that regulate energy, bile acid, glucose, lipid, phosphate, and vitamin D homeostasis in an endocrine fashion. Their activities require the presence of α or βKlotho, two related single-pass tran...

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Detalhes bibliográficos
Main Authors: Wu, Xinle, Lemon, Bryan, Li, XiaoFan, Gupte, Jamila, Weiszmann, Jennifer, Stevens, Jennitte, Hawkins, Nessa, Shen, Wenyan, Lindberg, Richard, Chen, Jin-Long, Tian, Hui, Li, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662259/
https://ncbi.nlm.nih.gov/pubmed/18829467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803319200
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