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Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice

FGF19 is a hormone that regulates bile acid and glucose homeostasis. Progress has been made in identifying cofactors for receptor activation. However, several functions of FGF19 have not yet been fully defined, including the actions of FGF19 on target tissues, its FGF receptor specificity, and the c...

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Main Authors: Wu, Xinle, Ge, Hongfei, Lemon, Bryan, Weiszmann, Jennifer, Gupte, Jamila, Hawkins, Nessa, Li, Xiaofan, Tang, Jie, Lindberg, Richard, Li, Yang
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726038/
https://ncbi.nlm.nih.gov/pubmed/19706524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907812106
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