Universal Immunoassay Applied During Early Development of Large Molecules to Understand Impact of Immunogenicity on Biotherapeutic Exposure

Por Bautista, Ami C., Salimi-Moosavi, Hossein, Jawa, Vibha
Publicado em 2012

Simultaneous Analysis of Multiple Monoclonal Antibody Biotherapeutics by LC-MS/MS Method in Rat Plasma Following Cassette-Dosing

Por Li, Hongyan, Ortiz, Robert, Tran, Linh T. B., Salimi-Moosavi, Hossein, Malella, Jennifer, James, Christopher A., Lee, Jean W.
Publicado em 2012

Pharmacokinetic comparison of a diverse panel of non-targeting human antibodies as matched IgG1 and IgG2 isotypes in rodents and non-human primates

Por Walker, Kenneth W., Salimi-Moosavi, Hossein, Arnold, Gregory E., Chen, Qing, Soto, Marcus, Jacobsen, Frederick W., Hui, John
Publicado no PLoS One (2019)

The serum protein transthyretin as a platform for dimerization and tetramerization of antibodies and Fab fragments to enable target clustering

Por Walker, Kenneth W., Foltz, Ian N., Wang, Tina, Salimi-Moosavi, Hossein, Bailis, Julie M., Lee, Fei, An, Phillip, Smith, Stephen, Bruno, Richele, Wang, Zhulun
Publicado no J Biol Chem (2020)

Rapid single B cell antibody discovery using nanopens and structured light

Por Winters, Aaron, McFadden, Karyn, Bergen, John, Landas, Julius, Berry, Kelly A., Gonzalez, Anthony, Salimi-Moosavi, Hossein, Murawsky, Christopher M., Tagari, Philip, King, Chadwick T.
Publicado no MAbs (2019)

Bioanalytical Approaches to Quantify “Total” and “Free” Therapeutic Antibodies and Their Targets: Technical Challenges and PK/PD Applications Over the Course of Drug Development...

Por Lee, Jean W., Kelley, Marian, King, Lindsay E., Yang, Jihong, Salimi-Moosavi, Hossein, Tang, Meina T., Lu, Jian-Feng, Kamerud, John, Ahene, Ago, Myler, Heather, Rogers, Cindy
Publicado em 2011

Engineering an IgG Scaffold Lacking Effector Function with Optimized Developability

Por Jacobsen, Frederick W., Stevenson, Riki, Li, Cynthia, Salimi-Moosavi, Hossein, Liu, Ling, Wen, Jie, Luo, Quanzhou, Daris, Kristine, Buck, Lynette, Miller, Sterling, Ho, Shu-Yin, Wang, Wei, Chen, Qing, Walker, Kenneth, Wypych, Jette, Narhi, Linda, Gunasekaran, Kannan
Publicado no J Biol Chem (2017)

Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice

Por Mao, Kai, Quipildor, Gabriela Farias, Tabrizian, Tahmineh, Novaj, Ardijana, Guan, Fangxia, Walters, Ryan O., Delahaye, Fabien, Hubbard, Gene B., Ikeno, Yuji, Ejima, Keisuke, Li, Peng, Allison, David B., Salimi-Moosavi, Hossein, Beltran, Pedro J., Cohen, Pinchas, Barzilai, Nir, Huffman, Derek M.
Publicado no Nat Commun (2018)

Inhibition of WISE Preserves Renal Allograft Function

Por Qian, Xueming, Yuan, Xiaodong, Vonderfecht, Steven, Ge, Xupeng, Lee, Jae, Jurisch, Anke, Zhang, Li, You, Andrew, Fitzpatrick, Vincent D., Williams, Alexia, Valente, Eliane G., Pretorius, Jim, Stevens, Jennitte L., Tipton, Barbara, Winters, Aaron G., Graham, Kevin, Harriss, Lindsey, Baker, Daniel M., Damore, Michael, Salimi-Moosavi, Hossein, Gao, Yongming, Elkhal, Abdallah, Paszty, Chris, Simonet, W. Scott, Richards, William G., Tullius, Stefan G.
Publicado em 2012

A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair

Por Florio, Monica, Gunasekaran, Kannan, Stolina, Marina, Li, Xiaodong, Liu, Ling, Tipton, Barbara, Salimi-Moosavi, Hossein, Asuncion, Franklin J., Li, Chaoyang, Sun, Banghua, Tan, Hong Lin, Zhang, Li, Han, Chun-Ya, Case, Ryan, Duguay, Amy N., Grisanti, Mario, Stevens, Jennitte, Pretorius, James K., Pacheco, Efrain, Jones, Heidi, Chen, Qing, Soriano, Brian D., Wen, Jie, Heron, Brenda, Jacobsen, Frederick W., Brisan, Emil, Richards, William G., Ke, Hua Zhu, Ominsky, Michael S.
Publicado no Nat Commun (2016)