Inhibition of WISE Preserves Renal Allograft Function

Wnt-modulator in surface ectoderm (WISE) is a secreted modulator of Wnt signaling expressed in the adult kidney. Activation of Wnt signaling has been observed in renal transplants developing interstitial fibrosis and tubular atrophy; however, whether WISE contributes to chronic changes is not well u...

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Detalhes bibliográficos
Main Authors: Qian, Xueming, Yuan, Xiaodong, Vonderfecht, Steven, Ge, Xupeng, Lee, Jae, Jurisch, Anke, Zhang, Li, You, Andrew, Fitzpatrick, Vincent D., Williams, Alexia, Valente, Eliane G., Pretorius, Jim, Stevens, Jennitte L., Tipton, Barbara, Winters, Aaron G., Graham, Kevin, Harriss, Lindsey, Baker, Daniel M., Damore, Michael, Salimi-Moosavi, Hossein, Gao, Yongming, Elkhal, Abdallah, Paszty, Chris, Simonet, W. Scott, Richards, William G., Tullius, Stefan G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2012
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537210/
https://ncbi.nlm.nih.gov/pubmed/23184054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012010012
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