Anabolic Strategies to Augment Bone Fracture Healing

nork Roberts, Scott J., Ke, Hua Zhu
Argitaratua izan da Curr Osteoporos Rep (2018)

Anti-sclerostin antibody and mechanical loading appear to influence metaphyseal bone independently in rats

nork Agholme, Fredrik, Isaksson, Hanna, Li, Xiaodong, Ke, Hua Zhu, Aspenberg, Per
Argitaratua 2011

Osteocyte Mechanosensing Following Short-Term and Long-Term Treatment with Sclerostin Antibody

nork Morrell, Andrea E., Robinson, Samuel T., Ke, Hua Zhu, Holdsworth, Gill, Guo, X. Edward
Argitaratua izan da Bone (2021)

The intracellular domain of CD44 promotes the fusion of macrophages

nork Cui, Weiguo, Ke, Juan Zhang, Zhang, Qing, Ke, Hua-Zhu, Chalouni, Cécile, Vignery, Agnès
Argitaratua 2006

Systemic Administration of Sclerostin Antibody Enhances Bone Repair in a Critical-Sized Femoral Defect in a Rat Model

nork Virk, Mandeep S., Alaee, Farhang, Tang, Hezhen, Ominsky, Michael S., Ke, Hua Zhu, Lieberman, Jay R.
Argitaratua 2013

Sclerostin Antibody Increases Bone Volume and Enhances Implant Fixation in a Rat Model

nork Virdi, Amarjit S., Liu, Min, Sena, Kotaro, Maletich, James, McNulty, Margaret, Ke, Hua Zhu, Sumner, Dale R.
Argitaratua 2012

Sclerostin Antibody Prevented Progressive Bone Loss in Combined Ovariectomized and Concurrent Functional Disuse

nork Zhang, Dongye, Hu, Minyi, Chu, Timothy, Lin, Liangjun, Wang, Jingyu, Li, Xiaodong, Ke, Hua Zhu, Qin, Yi-Xian
Argitaratua izan da Bone (2016)

Erratum to Sclerostin antibody prevented progressive bone loss in combined ovariectomized and concurrent functional disuse [Bone 87 (2016) 161–168]

nork Zhang, Dongye, Hu, Minyi, Chu, Timothy, Lin, Liangjun, Wang, Jingyu, Li, Xiaodong, Ke, Hua Zhu, Qin, Yi-Xian
Argitaratua izan da Bone (2016)

Sclerostin inhibition reverses systemic, periarticular and local bone loss in arthritis

nork Chen, Xiao-Xiang, Baum, Wolfgang, Dwyer, Denise, Stock, Michael, Schwabe, Kay, Ke, Hua-Zhu, Stolina, Marina, Schett, Georg, Bozec, Aline
Argitaratua 2013

IL-1 receptor–associated kinase M is a central regulator of osteoclast differentiation and activation

nork Li, Hongmei, Cuartas, Esteban, Cui, Weiguo, Choi, Yongwon, Crawford, Todd D., Ke, Hua Zhu, Kobayashi, Koichi S., Flavell, Richard A., Vignery, Agnès
Argitaratua 2005

ACTIVATION OF EXTRACELLULAR-SIGNAL REGULATED KINASE (ERK1/2) BY FLUID SHEAR IS CA(2+)- AND ATP-DEPENDENT IN MC3T3-E1 OSTEOBLASTS

nork Liu, Dawei, Genetos, Damian C., Shao, Ying, Geist, Derik J., Li, Jiliang, Ke, Hua Zhu, Turner, Charles H., Duncan, Randall L.
Argitaratua 2007

Recombinant sclerostin inhibits bone formation in vitro and in a mouse model of sclerosteosis

nork Dreyer, Timothy, Shah, Mittal, Doyle, Carl, Greenslade, Kevin, Penney, Mark, Creeke, Paul, Kotian, Apoorva, Ke, Hua Zhu, Naidoo, Vinny, Holdsworth, Gill
Argitaratua izan da J Orthop Translat (2021)

Anti-DKK1 antibody promotes bone fracture healing through activation of β-catenin signaling

nork Jin, Hongting, Wang, Baoli, Li, Jia, Xie, Wanqing, Mao, Qiang, Li, Shan, Dong, Fuqiang, Sun, Yan, Ke, Hua-Zhu, Babij, Philip, Tong, Peijian, Chen, Di
Argitaratua izan da Bone (2014)

Sclerostin Antibody Inhibits Skeletal Deterioration Due to Reduced Mechanical Loading

nork Spatz, Jordan M, Ellman, Rachel, Cloutier, Alison M, Louis, Leeann, van Vliet, Miranda, Suva, Larry J, Dwyer, Denise, Stolina, Marina, Ke, Hua Zhu, Bouxsein, Mary L
Argitaratua 2013

Retention of osteocytic micromorphology by sclerostin antibody in a concurrent ovariectomy and functional disuse model

nork Zhang, Dongye, Miranda, Marianna, Li, Xiaofei, Han, Jiangmeng, Sun, Yueli, Rojas, Nancy, He, Shan, Hu, Minyi, Lin, Liangjun, Li, Xiaodong, Ke, Hua Zhu, Qin, Yi-Xian
Argitaratua izan da Ann N Y Acad Sci (2019)

Sclerostin antibody administration converts bone lining cells into active osteoblasts

nork Kim, Sang Wan, Lu, Yanhui, Williams, Elizabeth A., Lai, Forest, Lee, Ji Yeon, Enishi, Tetsuya, Balani, Deepak H., Ominsky, Michael S., Ke, Hua Zhu, Kronenberg, Henry M., Wein, Marc N.
Argitaratua izan da J Bone Miner Res (2017)

Sclerostin Antibody Reverses the Severe Sublesional Bone Loss in Rats After Chronic Spinal Cord Injury

nork Zhao, Wei, Li, Xiaodong, Peng, Yuanzhen, Qin, Yiwen, Pan, Jiangping, Li, Jiliang, Xu, Aihua, Ominsky, Michael S., Cardozo, Christopher, Feng, Jian Q., Ke, Hua Zhu, Bauman, William A., Qin, Weiping
Argitaratua izan da Calcif Tissue Int (2018)

Sclerostin antibody treatment improves the bone phenotype of Crtap(−/−) mice, a model of recessive Osteogenesis Imperfecta

nork Grafe, Ingo, Alexander, Stefanie, Yang, Tao, Lietman, Caressa, Homan, Erica P, Munivez, Elda, Chen, Yuqing, Jiang, Ming Ming, Bertin, Terry, Dawson, Brian, Asuncion, Franklin, Ke, Hua Zhu, Ominsky, Michael S, Lee, Brendan
Argitaratua izan da J Bone Miner Res (2016)

Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis

nork Buckbinder, Leonard, Crawford, David T., Qi, Hong, Ke, Hua Zhu, Olson, Lisa M., Long, Kelly R., Bonnette, Peter C., Baumann, Amy P., Hambor, John E., Grasser, William A., Pan, Lydia C., Owen, Thomas A., Luzzio, Michael J., Hulford, Catherine A., Gebhard, David F., Paralkar, Vishwas M., Simmons, Hollis A., Kath, John C., Roberts, W. Gregory, Smock, Steven L., Guzman-Perez, Angel, Brown, Thomas A., Li, Mei
Argitaratua 2007

A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair

nork Florio, Monica, Gunasekaran, Kannan, Stolina, Marina, Li, Xiaodong, Liu, Ling, Tipton, Barbara, Salimi-Moosavi, Hossein, Asuncion, Franklin J., Li, Chaoyang, Sun, Banghua, Tan, Hong Lin, Zhang, Li, Han, Chun-Ya, Case, Ryan, Duguay, Amy N., Grisanti, Mario, Stevens, Jennitte, Pretorius, James K., Pacheco, Efrain, Jones, Heidi, Chen, Qing, Soriano, Brian D., Wen, Jie, Heron, Brenda, Jacobsen, Frederick W., Brisan, Emil, Richards, William G., Ke, Hua Zhu, Ominsky, Michael S.
Argitaratua izan da Nat Commun (2016)