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Sclerostin Antibody Prevented Progressive Bone Loss in Combined Ovariectomized and Concurrent Functional Disuse

Osteoporosis is characterized by low bone mass and compromised trabecular architecture, and is commonly occurred in post-menopausal women with estrogen deficiency. In addition, prolonged mechanical unloading, i.e., long term bed rest, can exaggerate the bone loss. Sclerostin is a Wnt signaling antag...

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Detalhes bibliográficos
Publicado no:Bone
Main Authors: Zhang, Dongye, Hu, Minyi, Chu, Timothy, Lin, Liangjun, Wang, Jingyu, Li, Xiaodong, Ke, Hua Zhu, Qin, Yi-Xian
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862887/
https://ncbi.nlm.nih.gov/pubmed/26868528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2016.02.005
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