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Sclerostin Antibody Prevented Progressive Bone Loss in Combined Ovariectomized and Concurrent Functional Disuse
Osteoporosis is characterized by low bone mass and compromised trabecular architecture, and is commonly occurred in post-menopausal women with estrogen deficiency. In addition, prolonged mechanical unloading, i.e., long term bed rest, can exaggerate the bone loss. Sclerostin is a Wnt signaling antag...
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| Veröffentlicht in: | Bone |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4862887/ https://ncbi.nlm.nih.gov/pubmed/26868528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2016.02.005 |
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