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Agonistic β-Klotho antibody mimics fibroblast growth factor 21 (FGF21) functions

Fibroblast growth factor 21 (FGF21), an endocrine hormone in the FGF family, plays a critical role in regulating metabolic homeostasis and has emerged as a therapeutic target for metabolic diseases, including Type 2 diabetes mellitus. FGF21 functions through a receptor complex that consists of an FG...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Min, Xiaoshan, Weiszmann, Jennifer, Johnstone, Sheree, Wang, Wei, Yu, Xinchao, Romanow, William, Thibault, Stephen, Li, Yang, Wang, Zhulun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153294/
https://ncbi.nlm.nih.gov/pubmed/30068552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004343
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