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Rational selection of building blocks for the assembly of bispecific antibodies

Bispecific antibodies, engineered to recognize two targets simultaneously, demonstrate exceptional clinical potential for the therapeutic intervention of complex diseases. However, these molecules are often composed of multiple polypeptide chains of differing sequences. To meet industrial scale prod...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Gong, Danyang, Riley, Timothy P., Bzymek, Krzysztof P., Correia, Ana R., Li, Danqing, Spahr, Christopher, Robinson, John H., Case, Ryan B., Wang, Zhulun, Garces, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808324/
https://ncbi.nlm.nih.gov/pubmed/33397191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2020.1870058
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