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Rational selection of building blocks for the assembly of bispecific antibodies

Bispecific antibodies, engineered to recognize two targets simultaneously, demonstrate exceptional clinical potential for the therapeutic intervention of complex diseases. However, these molecules are often composed of multiple polypeptide chains of differing sequences. To meet industrial scale prod...

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Bibliografische gegevens
Gepubliceerd in:MAbs
Hoofdauteurs: Gong, Danyang, Riley, Timothy P., Bzymek, Krzysztof P., Correia, Ana R., Li, Danqing, Spahr, Christopher, Robinson, John H., Case, Ryan B., Wang, Zhulun, Garces, Fernando
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808324/
https://ncbi.nlm.nih.gov/pubmed/33397191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2020.1870058
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