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Rational selection of building blocks for the assembly of bispecific antibodies

Bispecific antibodies, engineered to recognize two targets simultaneously, demonstrate exceptional clinical potential for the therapeutic intervention of complex diseases. However, these molecules are often composed of multiple polypeptide chains of differing sequences. To meet industrial scale prod...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Danyang Gong, Timothy P. Riley, Krzysztof P. Bzymek, Ana R. Correia, Danqing Li, Christopher Spahr, John H. Robinson, Ryan B. Case, Zhulun Wang, Fernando Garces
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Taylor & Francis Group 2021-01-01
Σειρά:mAbs
Θέματα:
Διαθέσιμο Online:https://www.tandfonline.com/doi/10.1080/19420862.2020.1870058
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