Deficiency in the Organic Cation Transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in Mice Abolishes Renal Secretion of Organic Cations

מאת Jonker, Johan W., Wagenaar, Els, van Eijl, Sven, Schinkel, Alfred H.
יצא לאור 2003

P-Glycoprotein Limits Oral Availability, Brain Penetration, and Toxicity of an Anionic Drug, the Antibiotic Salinomycin

מאת Lagas, Jurjen S., Sparidans, Rolf W., van Waterschoot, Robert A. B., Wagenaar, Els, Beijnen, Jos H., Schinkel, Alfred H.
יצא לאור 2008

Multidrug Transporter ABCG2/Breast Cancer Resistance Protein Secretes Riboflavin (Vitamin B(2)) into Milk

מאת van Herwaarden, Antonius E., Wagenaar, Els, Merino, Gracia, Jonker, Johan W., Rosing, Hilde, Beijnen, Jos H., Schinkel, Alfred H.
יצא לאור 2007

Reduced Hepatic Uptake and Intestinal Excretion of Organic Cations in Mice with a Targeted Disruption of the Organic Cation Transporter 1 (Oct1 [Slc22a1]) Gene

מאת Jonker, Johan W., Wagenaar, Els, Mol, Carla A. A. M., Buitelaar, Marije, Koepsell, Hermann, Smit, Johan W., Schinkel, Alfred H.
יצא לאור 2001

Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide is Dependent on Abcc2, Abcc3, and Oatp1a/1b

מאת Vasilyeva, Aksana, Durmus, Selvi, Li, Lie, Wagenaar, Els, Hu, Shuiying, Gibson, Alice A., Panetta, John C., Mani, Sridhar, Sparreboom, Alex, Baker, Sharyn D., Schinkel, Alfred H.
הוצא לאור ב Cancer Res (2015)

Organic anion transporting polypeptide 1a/1b–knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs

מאת van de Steeg, Evita, Wagenaar, Els, van der Kruijssen, Cornelia M.M., Burggraaff, Johanna E.C., de Waart, Dirk R., Elferink, Ronald P.J. Oude, Kenworthy, Kathryn E., Schinkel, Alfred H.
יצא לאור 2010

Midazolam metabolism in Cytochrome P450 3A knockout mice can be attributed to upregulated CYP2C enzymes

מאת van Waterschoot, Robert A.B., van Herwaarden, Antonius E., Lagas, Jurjen S., Sparidans, Rolf W., Wagenaar, Els, van der Kruijssen, Cornelia M.M., Goldstein, Joyce A., Zeldin, Darryl C., Beijnen, Jos H., Schinkel, Alfred H.
יצא לאור 2007

The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria

מאת Jonker, Johan W., Buitelaar, Marije, Wagenaar, Els, van der Valk, Martin A., Scheffer, George L., Scheper, Rik J., Plösch, Torsten, Kuipers, Folkert, Elferink, Ronald P. J. Oude, Rosing, Hilde, Beijnen, Jos H., Schinkel, Alfred H.
יצא לאור 2002

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

מאת Schinkel, Alfred H., Mayer, Ulrich, Wagenaar, Els, Mol, Carla A. A. M., van Deemter, Liesbeth, Smit, Jaap J. M., van der Valk, Martin A., Voordouw, Arie C., Spits, Hergen, van Tellingen, Olaf, Zijlmans, J. Mark J. M., Fibbe, Willem E., Borst, Piet
יצא לאור 1997

Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver

מאת van de Steeg, Evita, Stránecký, Viktor, Hartmannová, Hana, Nosková, Lenka, Hřebíček, Martin, Wagenaar, Els, van Esch, Anita, de Waart, Dirk R., Oude Elferink, Ronald P.J., Kenworthy, Kathryn E., Sticová, Eva, al-Edreesi, Mohammad, Knisely, A.S., Kmoch, Stanislav, Jirsa, Milan, Schinkel, Alfred H.
יצא לאור 2012

Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism

מאת van Herwaarden, Antonius E., Wagenaar, Els, van der Kruijssen, Cornelia M.M., van Waterschoot, Robert A.B., Smit, Johan W., Song, Ji-Ying, van der Valk, Martin A., van Tellingen, Olaf, van der Hoorn, José W.A., Rosing, Hilde, Beijnen, Jos H., Schinkel, Alfred H.
יצא לאור 2007