Systems Immunology: Learning the Rules of the Immune System

מאת Villani, Alexandra-Chloé, Sarkizova, Siranush, Hacohen, Nir
הוצא לאור ב Annu Rev Immunol (2018)

Targeting individual cells by barcode in pooled sequence libraries

מאת Ranu, Navpreet, Villani, Alexandra-Chloé, Hacohen, Nir, Blainey, Paul C
הוצא לאור ב Nucleic Acids Res (2019)

IL-12 and Mucosal CD14(+) Monocyte-Like Cells Induce IL-8 in Colonic Memory CD4(+) T Cells of Patients With Ulcerative Colitis but not Crohn’s Disease

מאת Chapuy, Laurence, Bsat, Marwa, Rubio, Manuel, Sarkizova, Sisi, Therrien, Amélie, Bouin, Mickael, Orlicka, Katarzina, Weber, Audrey, Soucy, Geneviève, Villani, Alexandra-Chloé, Sarfati, Marika
הוצא לאור ב J Crohns Colitis (2020)

Large-Scale Human Dendritic Cell Differentiation Revealing Notch-Dependent Lineage Bifurcation and Heterogeneity

מאת Balan, Sreekumar, Arnold-Schrauf, Catharina, Abbas, Abdenour, Couespel, Norbert, Savoret, Juliette, Imperatore, Francesco, Villani, Alexandra-Chloé, Vu Manh, Thien-Phong, Bhardwaj, Nina, Dalod, Marc
הוצא לאור ב Cell Rep (2018)

The Known Unknowns of the Immune Response to Coccidioides

מאת Ward, Rebecca A., Thompson, George R., Villani, Alexandra-Chloé, Li, Bo, Mansour, Michael K., Wuethrich, Marcel, Tam, Jenny M., Klein, Bruce S., Vyas, Jatin M.
הוצא לאור ב J Fungi (Basel) (2021)

Altered ratio of dendritic cell subsets in skin-draining lymph nodes promotes Th2-driven contact hypersensitivity

מאת Miller, Hannah L., Andhey, Prabhakar Sairam, Swiecki, Melissa K., Rosa, Bruce A., Zaitsev, Konstantin, Villani, Alexandra-Chloe, Mitreva, Makedonka, Artyomov, Maxim N., Gilfillan, Susan, Cella, Marina, Colonna, Marco
הוצא לאור ב Proc Natl Acad Sci U S A (2021)

Cumulus provides cloud-based data analysis for large-scale single-cell and single-nucleus RNA-seq

מאת Li, Bo, Gould, Joshua, Yang, Yiming, Sarkizova, Siranush, Tabaka, Marcin, Ashenberg, Orr, Rosen, Yanay, Slyper, Michal, Kowalczyk, Monika S, Villani, Alexandra-Chloé, Tickle, Timothy, Hacohen, Nir, Rozenblatt-Rosen, Orit, Regev, Aviv
הוצא לאור ב Nat Methods (2020)

The Incidence, Causes, and Risk Factors of Acute Kidney Injury in Patients Receiving Immune Checkpoint Inhibitors

מאת Seethapathy, Harish, Zhao, Sophia, Chute, Donald F., Zubiri, Leyre, Oppong, Yaa, Strohbehn, Ian, Cortazar, Frank B., Leaf, David E., Mooradian, Meghan J., Villani, Alexandra-Chloé, Sullivan, Ryan J., Reynolds, Kerry, Sise, Meghan E.
הוצא לאור ב Clin J Am Soc Nephrol (2019)

Transcriptomic Analysis and High-dimensional Phenotypic Mapping of Mononuclear Phagocytes in Mesenteric Lymph Nodes Reveal Differences Between Ulcerative Colitis and Crohn’s Diseas...

מאת Chapuy, Laurence, Bsat, Marwa, Rubio, Manuel, Harvey, François, Motta, Vinicius, Schwenter, Frank, Wassef, Ramses, Richard, Carole, Deslandres, Colette, Nguyen, Bich N, Soucy, Geneviève, Hacohen, Nir, Fritz, Jorge, Villani, Alexandra-Chloé, Mehta, Heena, Sarfati, Marika
הוצא לאור ב J Crohns Colitis (2020)

SLAMF6​ deficiency augments tumor killing and skews toward an effector phenotype revealing it as a novel T cell checkpoint

מאת Hajaj, Emma, Eisenberg, Galit, Klein, Shiri, Frankenburg, Shoshana, Merims, Sharon, Ben David, Inna, Eisenhaure, Thomas, Henrickson, Sarah E, Villani, Alexandra Chloé, Hacohen, Nir, Abudi, Nathalie, Abramovich, Rinat, Cohen, Jonathan E, Peretz, Tamar, Veillette, Andre, Lotem, Michal
הוצא לאור ב eLife (2020)

Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach

מאת Lee, Mark N, Roy, Matthew, Ong, Shao-En, Mertins, Philipp, Villani, Alexandra-Chloé, Li, Weibo, Dotiwala, Farokh, Sen, Jayita, Doench, John G, Orzalli, Megan H, Kramnik, Igor, Knipe, David M, Lieberman, Judy, Carr, Steven A, Hacohen, Nir
יצא לאור 2012

Decreased Absolute Lymphocyte Count and Increased Neutrophil/Lymphocyte Ratio With Immune Checkpoint Inhibitor–Associated Myocarditis

מאת Drobni, Zsofia D., Zafar, Amna, Zubiri, Leyre, Zlotoff, Daniel A., Alvi, Raza M., Lee, Charlotte, Hartmann, Sarah, Gilman, Hannah K., Villani, Alexandra‐Chloe, Nohria, Anju, Groarke, John D., Sullivan, Ryan J., Reynolds, Kerry L., Zhang, Lili, Neilan, Tomas G.
הוצא לאור ב J Am Heart Assoc (2020)

Incidence and Clinical Features of Immune-Related Acute Kidney Injury in Patients Receiving Programmed Cell Death Ligand-1 Inhibitors

מאת Seethapathy, Harish, Zhao, Sophia, Strohbehn, Ian A., Lee, Meghan, Chute, Donald F., Bates, Halla, Molina, Gabriel E., Zubiri, Leyre, Gupta, Shruti, Motwani, Shveta, Leaf, David E., Sullivan, Ryan J., Rahma, Osama, Blumenthal, Kimberly G., Villani, Alexandra-Chloe, Reynolds, Kerry L., Sise, Meghan E.
הוצא לאור ב Kidney Int Rep (2020)

Immune-related adverse events associated with immune checkpoint inhibitors: a call to action for collecting and sharing clinical trial and real-world data

מאת Reynolds, Kerry L, Arora, Shaily, Elayavilli, Ravikumar Komandur, Louv, William C, Schaller, Teilo H, Khandelwal, Aakanksha, Rothenberg, Mace, Khozin, Sean, Guidon, Amanda C, Dougan, Michael, Zubiri, Leyre, Petrillo, Laura, Sise, Meghan E, Villani, Alexandra-Chloe, Johnson, Douglas B, Rahma, Osama, Sharon, Elad
הוצא לאור ב J Immunother Cancer (2021)

Targeting the CBM complex causes Treg cells to prime tumors for immune checkpoint therapy

מאת Pilato, Mauro Di, Kim, Edward Y., Cadilha, Bruno L., Pruessmann, Jasper N., Nasrallah, Mazen N., Seruggia, Davide, Usmani, Shariq M., Misale, Sandra, Zappulli, Valentina, Carrizosa, Esteban, Mani, Vinidhra, Ligorio, Matteo, Warner, Ross D., Medoff, Benjamin D., Marangoni, Francesco, Villani, Alexandra-Chloe, Mempel, Thorsten R.
הוצא לאור ב Nature (2019)

The activation trajectory of plasmacytoid dendritic cells in vivo during a viral infection

מאת Abbas, Abdenour, Manh, Thien-Phong Vu, Valente, Michael, Collinet, Nils, Attaf, Noudjoud, Dong, Chuang, Naciri, Karima, Chelbi, Rabie, Brelurut, Geoffray, Cervera-Marzal, Inaki, Rauwel, Benjamin, Davignon, Jean-Luc, Bessou, Gilles, Thomas-Chollier, Morgane, Thieffry, Denis, Villani, Alexandra-Chloé, Milpied, Pierre, Dalod, Marc, Tomasello, Elena
הוצא לאור ב Nat Immunol (2020)

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility

מאת Villani, Alexandra-Chloé, Lemire, Mathieu, Fortin, Geneviève, Louis, Edouard, Silverberg, Mark S, Collette, Catherine, Baba, Nobuyasu, Libioulle, Cécile, Belaiche, Jacques, Bitton, Alain, Gaudet, Daniel, Cohen, Albert, Langelier, Diane, Fortin, Paul R, Wither, Joan E, Sarfati, Marika, Rutgeerts, Paul, Rioux, John D, Vermeire, Severine, Hudson, Thomas J, Franchimont, Denis
יצא לאור 2008

Landscape of X chromosome inactivation across human tissues

מאת Tukiainen, Taru, Villani, Alexandra-Chloé, Yen, Angela, Rivas, Manuel A., Marshall, Jamie L., Satija, Rahul, Aguirre, Matt, Gauthier, Laura, Fleharty, Mark, Kirby, Andrew, Cummings, Beryl B., Castel, Stephane E., Karczewski, Konrad J., Aguet, François, Byrnes, Andrea, Lappalainen, Tuuli, Regev, Aviv, Ardlie, Kristin G., Hacohen, Nir, MacArthur, Daniel G.
הוצא לאור ב Nature (2017)

Induction of a regulatory myeloid program in bacterial sepsis and severe COVID-19

מאת Reyes, Miguel, Filbin, Michael R., Bhattacharyya, Roby P., Sonny, Abraham, Mehta, Arnav, Billman, Kianna, Kays, Kyle R., Pinilla-Vera, Mayra, Benson, Maura E., Cosimi, Lisa A., Hung, Deborah T., Levy, Bruce D., Villani, Alexandra-Chloe, Sade-Feldman, Moshe, Baron, Rebecca M., Goldberg, Marcia B., Blainey, Paul C., Hacohen, Nir
הוצא לאור ב bioRxiv (2020)

A transcriptomic atlas of aged human microglia

מאת Olah, Marta, Patrick, Ellis, Villani, Alexandra-Chloe, Xu, Jishu, White, Charles C., Ryan, Katie J., Piehowski, Paul, Kapasi, Alifiya, Nejad, Parham, Cimpean, Maria, Connor, Sarah, Yung, Christina J., Frangieh, Michael, McHenry, Allison, Elyaman, Wassim, Petyuk, Vlad, Schneider, Julie A., Bennett, David A., De Jager, Philip L., Bradshaw, Elizabeth M.
הוצא לאור ב Nat Commun (2018)