Moonshot Objectives: Catalyze New Scientific Breakthroughs – Proteogenomics

Por Rodland, Karin D., Piehowski, Paul, Smith, Richard
Publicado no Cancer J (2018)

Advances in microscale separations towards nanoproteomics applications

Por Yi, Lian, Piehowski, Paul D., Shi, Tujin, Smith, Richard D., Qian, Wei-Jun
Publicado no J Chromatogr A (2017)

Mass spectrometry imaging of mating Tetrahymena show that changes in cell morphology regulate lipid domain formation

Por Kurczy, Michael E., Piehowski, Paul D., Van Bell, Craig T., Heien, Michael L., Winograd, Nicolas, Ewing, Andrew G.
Publicado em 2010

Freeze-Etching and Vapor Matrix Deposition for ToF-SIMS Imaging of Single Cells

Por Piehowski, Paul D., Kurczy, Michael E., Willingham, David, Parry, Shawn, Heien, Michael L., Winograd, Nicholas, Ewing, Andrew G.
Publicado em 2008

Nanotome Cluster Bombardment to Recover Spatial Chemistry after Preparation of Biological Samples for SIMS Imaging

Por Kurczy, Michael E., Piehowski, Paul D., Willingham, David, Molyneaux, Kathleen A., Heien, Michael L., Winograd, Nicholas, Ewing, Andrew G.
Publicado em 2010

MS/MS Methodology to Improve Sub-Cellular Mapping of Cholesterol Using ToF-SIMS

Por Piehowski, Paul D., Carado, Anthony J., Kurczy, Michael E., Ostrowski, Sara G., Heien, Michael L., Winograd, Nicholas, Ewing, Andrew G.
Publicado em 2008

ToF-SIMS Imaging of Sub-Cellular Lipid Heterogeneity: Poisson Counting and Spatial Resolution

Por Piehowski, Paul D., Davey, Angel M., Kurczy, Michael E., Sheets, Erin D., Winograd, Nicholas, Ewing, Andrew G., Heien, Michael L.
Publicado em 2009

Deficient Expression of Aldehyde Dehydrogenase 1A1 is Consistent With Increased Sensitivity of Gorlin Syndrome Patients to Radiation Carcinogenesis

Por Wright, Aaron T., Magnaldo, Thierry, Sontag, Ryan L., Anderson, Lindsey N., Sadler, Natalie C., Piehowski, Paul D., Gache, Yannick, Weber, Thomas J.
Publicado no Mol Carcinog (2013)

A unique deubiquitinase that deconjugates phosphoribosyl-linked protein ubiquitination

Por Qiu, Jiazhang, Yu, Kaiwen, Fei, Xiaowen, Liu, Yao, Nakayasu, Ernesto S, Piehowski, Paul D, Shaw, Jared B, Puvar, Kedar, Das, Chittaranjan, Liu, Xiaoyun, Luo, Zhao-Qing
Publicado no Cell Res (2017)

Subnanogram proteomics: impact of LC column selection, MS instrumentation and data analysis strategy on proteome coverage for trace samples

Por Zhu, Ying, Zhao, Rui, Piehowski, Paul D., Moore, Ronald J., Lim, Sujung, Orphan, Victoria J., Paša-Tolić, Ljiljana, Qian, Wei-Jun, Smith, Richard D., Kelly, Ryan T.
Publicado no Int J Mass Spectrom (2017)

Steps: A Grid Search Methodology for Optimized Peptide Identification Filtering of MS/MS Database Search Results

Por Piehowski, Paul D., Petyuk, Vladislav A., Sandoval, John D., Burnum, Kristin E., Kiebel, Gary R., Monroe, Matthew E., Anderson, Gordon A., Camp, David G., Smith, Richard D.
Publicado em 2013

SNaPP: Simplified Nanoproteomics Platform for Reproducible Global Proteomic Analysis of Nanogram Protein Quantities

Por Huang, Eric L., Piehowski, Paul D., Orton, Daniel J., Moore, Ronald J., Qian, Wei-Jun, Casey, Cameron P., Sun, Xiaofei, Dey, Sudhansu K., Burnum-Johnson, Kristin E., Smith, Richard D.
Publicado no Endocrinology (2016)

High‐throughput serum proteomics for the identification of protein biomarkers of mortality in older men

Por Orwoll, Eric S., Wiedrick, Jack, Jacobs, Jon, Baker, Erin S., Piehowski, Paul, Petyuk, Vladislav, Gao, Yuqian, Shi, Tujin, Smith, Richard D., Bauer, Douglas C., Cummings, Steven R, Nielson, Carrie M., Lapidus, Jodi
Publicado no Aging Cell (2018)

Sources of Technical Variability in Quantitative LC-MS Proteomics: Human Brain Tissue Sample Analysis

Por Piehowski, Paul D., Petyuk, Vladislav A., Orton, Daniel J., Xie, Fang, Ramirez-Restrepo, Manuel, Engel, Anzhelika, Lieberman, Andrew P., Albin, Roger L., Camp, David G., Smith, Richard D., Myers, Amanda J.
Publicado em 2013

Microscale depletion of high abundance proteins in human biofluids using IgY14 immunoaffinity resin: analysis of human plasma and cerebrospinal fluid

Por Hyung, Seok-Won, Piehowski, Paul D., Moore, Ronald J., Orton, Daniel J., Schepmoes, Athena A., Clauss, Therese R., Chu, Rosalie K., Fillmore, Thomas L., Brewer, Heather, Liu, Tao, Zhao, Rui, Smith, Richard D.
Publicado em 2014

Nanodroplet processing platform for deep and quantitative proteome profiling of 10–100 mammalian cells

Por Zhu, Ying, Piehowski, Paul D., Zhao, Rui, Chen, Jing, Shen, Yufeng, Moore, Ronald J., Shukla, Anil K., Petyuk, Vladislav A., Campbell-Thompson, Martha, Mathews, Clayton E., Smith, Richard D., Qian, Wei-Jun, Kelly, Ryan T.
Publicado no Nat Commun (2018)

Increasing Confidence of LC-MS Identifications by Utilizing Ion Mobility Spectrometry

Por Crowell, Kevin L., Baker, Erin S., Payne, Samuel H., Ibrahim, Yehia M., Monroe, Matthew E., Slysz, Gordon W., LaMarche, Brian L., Petyuk, Vladislav A., Piehowski, Paul D., Danielson, William F., Anderson, Gordon A., Smith, Richard D.
Publicado em 2013

Muscle Segment Homeobox Genes Direct Embryonic Diapause by Limiting Inflammation in the Uterus

Por Cha, Jeeyeon, Burnum-Johnson, Kristin E., Bartos, Amanda, Li, Yingju, Baker, Erin S., Tilton, Susan C., Webb-Robertson, Bobbie-Jo M., Piehowski, Paul D., Monroe, Matthew E., Jegga, Anil G., Murata, Shigeo, Hirota, Yasushi, Dey, Sudhansu K.
Publicado no J Biol Chem (2015)

Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL hotspots, splicing QTLs and novel non-coding genes

Por Hasin-Brumshtein, Yehudit, Khan, Arshad H, Hormozdiari, Farhad, Pan, Calvin, Parks, Brian W, Petyuk, Vladislav A, Piehowski, Paul D, Brümmer, Anneke, Pellegrini, Matteo, Xiao, Xinshu, Eskin, Eleazar, Smith, Richard D, Lusis, Aldons J, Smith, Desmond J
Publicado no eLife (2016)

Spatially-Resolved Proteomics: Rapid Quantitative Analysis of Laser Capture Microdissected Alveolar Tissue Samples

Por Clair, Geremy, Piehowski, Paul D., Nicola, Teodora, Kitzmiller, Joseph A., Huang, Eric L., Zink, Erika M., Sontag, Ryan L., Orton, Daniel J., Moore, Ronald J., Carson, James P., Smith, Richard D., Whitsett, Jeffrey A., Corley, Richard A., Ambalavanan, Namasivayam, Ansong, Charles
Publicado no Sci Rep (2016)