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MS/MS Methodology to Improve Sub-Cellular Mapping of Cholesterol Using ToF-SIMS

Time-of-flight secondary ion mass spectrometry (ToF-SIMS) can be utilized to map the distribution of various molecules on a surface with sub-micrometer resolution. Much of its biological application has been in the study of membrane lipids, such as phospholipids and cholesterol. Cholesterol is a par...

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Bibliographic Details
Main Authors: Piehowski, Paul D., Carado, Anthony J., Kurczy, Michael E., Ostrowski, Sara G., Heien, Michael L., Winograd, Nicholas, Ewing, Andrew G.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597061/
https://ncbi.nlm.nih.gov/pubmed/18925746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac801591r
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