Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL hotspots, splicing QTLs and novel non-coding genes

Previous studies had shown that the integration of genome wide expression profiles, in metabolic tissues, with genetic and phenotypic variance, provided valuable insight into the underlying molecular mechanisms. We used RNA-Seq to characterize hypothalamic transcriptome in 99 inbred strains of mice...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Hasin-Brumshtein, Yehudit, Khan, Arshad H, Hormozdiari, Farhad, Pan, Calvin, Parks, Brian W, Petyuk, Vladislav A, Piehowski, Paul D, Brümmer, Anneke, Pellegrini, Matteo, Xiao, Xinshu, Eskin, Eleazar, Smith, Richard D, Lusis, Aldons J, Smith, Desmond J
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Genomics and Evolutionary Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053804/
https://ncbi.nlm.nih.gov/pubmed/27623010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15614
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