Transcriptomic Analysis and High-dimensional Phenotypic Mapping of Mononuclear Phagocytes in Mesenteric Lymph Nodes Reveal Differences Between Ulcerative Colitis and Crohn’s Disease

BACKGROUND AND AIMS: Crohn’s disease [CD] and ulcerative colitis [UC] are distinct forms of inflammatory bowel disease. Heterogeneity of HLA-DR(+)SIRPα (+) mononuclear phagocytes [MNPs], including macrophages [MΦ], monocyte-derived [Mono] cells, and dendritic cells [DCs], was reported in gut tissue...

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Detalhes bibliográficos
Publicado no:J Crohns Colitis
Main Authors: Chapuy, Laurence, Bsat, Marwa, Rubio, Manuel, Harvey, François, Motta, Vinicius, Schwenter, Frank, Wassef, Ramses, Richard, Carole, Deslandres, Colette, Nguyen, Bich N, Soucy, Geneviève, Hacohen, Nir, Fritz, Jorge, Villani, Alexandra-Chloé, Mehta, Heena, Sarfati, Marika
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7068244/
https://ncbi.nlm.nih.gov/pubmed/31541232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjz156
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