Targeting the CBM complex causes Treg cells to prime tumors for immune checkpoint therapy

Solid tumors are infiltrated by effector T cells (Teff) with the potential to control or reject them, as well as by regulatory T cells (Treg) that restrict the function of Teff and thereby promote tumor growth.(1) The anti-tumor activity of Teff can be therapeutically unleashed and is now being expl...

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Detaylı Bibliyografya
Yayımlandı:Nature
Asıl Yazarlar: Pilato, Mauro Di, Kim, Edward Y., Cadilha, Bruno L., Pruessmann, Jasper N., Nasrallah, Mazen N., Seruggia, Davide, Usmani, Shariq M., Misale, Sandra, Zappulli, Valentina, Carrizosa, Esteban, Mani, Vinidhra, Ligorio, Matteo, Warner, Ross D., Medoff, Benjamin D., Marangoni, Francesco, Villani, Alexandra-Chloe, Mempel, Thorsten R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656391/
https://ncbi.nlm.nih.gov/pubmed/31092922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1215-2
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