Tumour Suppressor Mechanisms in the Control of Chromosome Stability: Insights from BRCA2

Por Venkitaraman, Ashok R.
Publicado em 2014

Two modules in the BRC repeats of BRCA2 mediate structural and functional interactions with the RAD51 recombinase

Por Rajendra, Eeson, Venkitaraman, Ashok R.
Publicado em 2010

Micro(mi) RNA-34a targets protein phosphatase (PP)1γ to regulate DNA damage tolerance

Por Takeda, Yuko, Venkitaraman, Ashok R
Publicado no Cell Cycle (2015)

Oncogenic KRAS triggers MAPK-dependent errors in mitosis and MYC-dependent sensitivity to anti-mitotic agents

Por Perera, David, Venkitaraman, Ashok R.
Publicado no Sci Rep (2016)

Inhibition of Interleukin 7 Receptor Signaling by Antigen Receptor Assembly

Por Smart, Fiona M., Venkitaraman, Ashok R.
Publicado em 2000

A vertebrate N-end rule degron reveals that Orc6 is required in mitosis for daughter cell abscission

Por Bernal, Juan A., Venkitaraman, Ashok R.
Publicado em 2011

A cancer-associated mutation inactivates a region of the high-mobility group protein HMG20b essential for cytokinesis

Por Lee, MiYoung, Venkitaraman, Ashok R
Publicado no Cell Cycle (2014)

Maximizing the Biochemical Resolving Power of Fluorescence Microscopy

Por Esposito, Alessandro, Popleteeva, Marina, Venkitaraman, Ashok R.
Publicado em 2013

Context dependence of Checkpoint kinase 1 as a therapeutic target for pancreatic cancers deficient in the BRCA2 tumour suppressor

Por Hattori, Hiroyoshi, Skoulidis, Ferdinandos, Russell, Paul, Venkitaraman, Ashok R.
Publicado em 2011

Cdk1 promotes kinetochore bi-orientation and regulates Cdc20 expression during recovery from spindle checkpoint arrest

Por Liang, Hongqing, Lim, Hong Hwa, Venkitaraman, Ashok, Surana, Uttam
Publicado em 2012

Chromosome instability and carcinogenesis: Insights from murine models of human pancreatic cancer associated with BRCA2 inactivation

Por Cassidy, Liam D., Liau, Siong-Seng, Venkitaraman, Ashok R.
Publicado em 2013

Rational Methods for the Selection of Diverse Screening Compounds

Por Huggins, David J., Venkitaraman, Ashok R., Spring, David R.
Publicado no ACS Chem Biol (2011)

Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein

Por Lomonosov, Mikhail, Anand, Shubha, Sangrithi, Mahesh, Davies, Rachel, Venkitaraman, Ashok R.
Publicado em 2003

Continuous polo-like kinase 1 activity regulates diffusion to maintain centrosome self-organization during mitosis

Por Mahen, Robert, Jeyasekharan, Anand D., Barry, Nicholas P., Venkitaraman, Ashok R.
Publicado em 2011

The Carboxyl Terminus of Brca2 Links the Disassembly of Rad51 Complexes to Mitotic Entry

Por Ayoub, Nabieh, Rajendra, Eeson, Su, Xinyi, Jeyasekharan, Anand D., Mahen, Robert, Venkitaraman, Ashok R.
Publicado em 2009

A-Type Lamins Maintain the Positional Stability of DNA Damage Repair Foci in Mammalian Nuclei

Por Mahen, Robert, Hattori, Hiroyoshi, Lee, Miyoung, Sharma, Pooja, Jeyasekharan, Anand D., Venkitaraman, Ashok R.
Publicado em 2013

Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions

Por Laraia, Luca, McKenzie, Grahame, Spring, David R., Venkitaraman, Ashok R., Huggins, David J.
Publicado no Chem Biol (2015)

p53 shapes genome-wide and cell type-specific changes in microRNA expression during the human DNA damage response

Por Hattori, Hiroyoshi, Janky, Rekin’s, Nietfeld, Wilfried, Aerts, Stein, Madan Babu, M, Venkitaraman, Ashok R
Publicado no Cell Cycle (2014)

Homeostatic control of polo-like kinase-1 engenders non-genetic heterogeneity in G2 checkpoint fidelity and timing

Por Liang, Hongqing, Esposito, Alessandro, De, Siddharth, Ber, Suzan, Collin, Philippe, Surana, Uttam, Venkitaraman, Ashok R.
Publicado em 2014

Small-Molecule Inhibitors That Target Protein–Protein Interactions in the RAD51 Family of Recombinases

Por Scott, Duncan E, Coyne, Anthony G, Venkitaraman, Ashok, Blundell, Tom L, Abell, Chris, Hyvönen, Marko
Publicado no ChemMedChem (2015)