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Tumour Suppressor Mechanisms in the Control of Chromosome Stability: Insights from BRCA2

Cancer is unique amongst human diseases in that its cellular manifestations arise and evolve through the acquisition of somatic alterations in the genome. In particular, instability in the number and structure of chromosomes is a near-universal feature of the genomic alterations associated with epit...

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Autor principal: Venkitaraman, Ashok R.
Format: Artigo
Idioma:Inglês
Publicat: Korea Society for Molecular and Cellular Biology 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935635/
https://ncbi.nlm.nih.gov/pubmed/24598993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2014.2346
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