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Inhibition of Interleukin 7 Receptor Signaling by Antigen Receptor Assembly

After the productive rearrangement of immunoglobulin (Ig) heavy chain genes, precursor (pre-)B lymphocytes undergo a limited number of cell divisions in response to interleukin (IL)-7. Here, we present evidence that this phase of IL-7–dependent expansion is constrained by an inhibitory signal initia...

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Autores principales: Smart, Fiona M., Venkitaraman, Ashok R.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195828/
https://ncbi.nlm.nih.gov/pubmed/10684865
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