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Cdk1 promotes kinetochore bi-orientation and regulates Cdc20 expression during recovery from spindle checkpoint arrest

The spindle assembly checkpoint (SAC), an evolutionarily conserved surveillance pathway, prevents chromosome segregation in response to conditions that disrupt the kinetochore-microtubule attachment. Removal of the checkpoint-activating stimulus initiates recovery during which spindle integrity is r...

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Detalhes bibliográficos
Main Authors: Liang, Hongqing, Lim, Hong Hwa, Venkitaraman, Ashok, Surana, Uttam
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261552/
https://ncbi.nlm.nih.gov/pubmed/22056777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.385
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