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Continuous polo-like kinase 1 activity regulates diffusion to maintain centrosome self-organization during mitosis
Whether mitotic structures like the centrosome can self-organize from the regulated mobility of their dynamic protein components remains unclear. Here, we combine fluorescence spectroscopy and chemical genetics to study in living cells the diffusion of polo-like kinase 1 (PLK1), an enzyme critical f...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107272/ https://ncbi.nlm.nih.gov/pubmed/21576470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101112108 |
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