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Ubiquitination-dependent localization of Polo-like kinase 1 in mitosis
Polo-like kinase 1 (PLK1) critically regulates mitosis through its dynamic localization to kinetochores, centrosomes and the midzone. The polo-box domain (PBD) and activity of PLK1 mediates its targeting to mitotic structures, but the mechanisms regulating PLK1 dynamics remain poorly understood. Her...
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| Publicado no: | Nat Cell Biol |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7116173/ https://ncbi.nlm.nih.gov/pubmed/23455478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2695 |
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