Ubiquitination-dependent localization of Polo-like kinase 1 in mitosis

Polo-like kinase 1 (PLK1) critically regulates mitosis through its dynamic localization to kinetochores, centrosomes and the midzone. The polo-box domain (PBD) and activity of PLK1 mediates its targeting to mitotic structures, but the mechanisms regulating PLK1 dynamics remain poorly understood. Her...

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Bibliografiska uppgifter
I publikationen:Nat Cell Biol
Huvudupphovsmän: Beck, Jochen, Maerki, Sarah, Posch, Markus, Metzger, Thibaud, Persaud, Avinash, Scheel, Hartmut, Hofmann, Kay, Rotin, Daniela, Pedrioli, Patrick, Swedlow, Jason R., Peter, Matthias, Sumara, Izabela
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116173/
https://ncbi.nlm.nih.gov/pubmed/23455478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2695
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