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Polo-like kinase 4 maintains centriolar satellite integrity by phosphorylation of centrosomal protein 131 (CEP131)

The centrosome, consisting of two centrioles surrounded by a dense network of proteins, is the microtubule-organizing center of animal cells. Polo-like kinase 4 (PLK4) is a Ser/Thr protein kinase and the master regulator of centriole duplication, but it may play additional roles in centrosome functi...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Denu, Ryan A., Sass, Madilyn M., Johnson, James M., Potts, Gregory K., Choudhary, Alka, Coon, Joshua J., Burkard, Mark E.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484138/
https://ncbi.nlm.nih.gov/pubmed/30804208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004867
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