Understanding Human Variation in Infectious Disease Susceptibility through Clinical and Cellular GWAS

Por Ko, Dennis C., Urban, Thomas J.
Publicado em 2013

Genetic basis of susceptibility to drug-induced liver injury: what have we learned and where do we go from here?

Por Urban, Thomas J., Goldstein, David B., Watkins, Paul B.
Publicado em 2012

Interferon-λ4 is a cell-autonomous type III interferon associated with pre-treatment hepatitis C virus burden

Por Lu, Yi-Fan, Goldstein, David B., Urban, Thomas J., Bradrick, Shelton S.
Publicado no Virology (2015)

Toward Predicting Drug-Induced Liver Injury: Parallel Computational Approaches to Identify Multidrug Resistance Protein 4 and Bile Salt Export Pump Inhibitors

Por Welch, Matthew A., Köck, Kathleen, Urban, Thomas J., Brouwer, Kim L. R., Swaan, Peter W.
Publicado no Drug Metab Dispos (2015)

Impact of the Interaction between 3′-UTR SNPs and microRNA on the Expression of Human Xenobiotic Metabolism Enzyme and Transporter Genes

Por Wei, Rongrong, Yang, Fan, Urban, Thomas J., Li, Lang, Chalasani, Naga, Flockhart, David A., Liu, Wanqing
Publicado em 2012

Prevalence of genetic variants of keratins 8 and 18 in patients with drug-induced liver injury

Por Usachov, Valentyn, Urban, Thomas J., Fontana, Robert J., Gross, Annika, Iyer, Sapna, Omary, M. Bishr, Strnad, Pavel
Publicado no BMC Med (2015)

IFNL3 mRNA structure is remodeled by a functional non-coding polymorphism associated with hepatitis C virus clearance

Por Lu, Yi-Fan, Mauger, David M., Goldstein, David B., Urban, Thomas J., Weeks, Kevin M., Bradrick, Shelton S.
Publicado no Sci Rep (2015)

WGAViewer: Software for genomic annotation of whole genome association studies

Por Ge, Dongliang, Zhang, Kunlin, Need, Anna C., Martin, Olivier, Fellay, Jacques, Urban, Thomas J., Telenti, Amalio, Goldstein, David B.
Publicado em 2008

Organic Anion Transporter 2 (SLC22A7) Is a Facilitative Transporter of cGMP

Por Cropp, Cheryl D., Komori, Takafumi, Shima, James E., Urban, Thomas J., Yee, Sook Wah, More, Swati S., Giacomini, Kathleen M.
Publicado em 2008

IL28B Genotype Effects During Early Treatment with Peginterferon and Ribavirin in Difficult-to-Treat Hepatitis C Virus Infection

Por Scott, John, Holte, Sarah, Urban, Thomas, Burgess, Caitlin, Coppel, Erica, Wang, Chia, Corey, Larry, McHutchison, John, Goldstein, David
Publicado em 2011

The Organic Cation Transporter, OCTN1, Expressed in the Human Heart, Potentiates Antagonism of the HERG Potassium Channel

Por McBride, Brian F., Yang, Tao, Liu, Kai, Urban, Thomas J., Giacomini, Kathleen M., Kim, Richard B., Roden, Dan M.
Publicado em 2009

Features of Autoimmune Hepatitis in Patients With Drug-induced Liver Injury

Por de Boer, Ynto S., Kosinski, Andrzej S., Urban, Thomas J., Zhao, Zhen, Long, Nanye, Chalasani, Naga, Kleiner, David E., Hoofnagle, Jay H.
Publicado no Clin Gastroenterol Hepatol (2016)

Functional genomics of membrane transporters in human populations

Por Urban, Thomas J., Sebro, Ronnie, Hurowitz, Evan H., Leabman, Maya K., Badagnani, Ilaria, Lagpacan, Leah L., Risch, Neil, Giacomini, Kathleen M.
Publicado em 2006

Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4

Por Köck, Kathleen, Ferslew, Brian C., Netterberg, Ida, Yang, Kyunghee, Urban, Thomas J., Swaan, Peter W., Stewart, Paul W., Brouwer, Kim L. R.
Publicado em 2014

Effects of Age, Sex, Body Weight, and Quantity of Alcohol Consumption on Occurrence and Severity of Alcoholic Hepatitis

Por Liangpunsakul, Suthat, Puri, Puneet, Shah, Vijay, Kamath, Patrick, Sanyal, Arun, Urban, Thomas, Ren, Xiaowei, Katz, Barry, Radaeva, Svetlana, Chalasani, Naga, Crabb, David W.
Publicado no Clin Gastroenterol Hepatol (2016)

Genetic and environmental correlates of topiramate-induced cognitive impairment

Por Cirulli, Elizabeth T., Urban, Thomas J., Marino, Susan E., Linney, Kristen N., Birnbaum, Angela K., Depondt, Chantal, Attix, Deborah K., Radtke, Rodney A., Goldstein, David B.
Publicado em 2011

A nonsense mutation in IKBKB causes combined immunodeficiency

Por Mousallem, Talal, Yang, Jialong, Urban, Thomas J., Wang, Hongxia, Adeli, Mehdi, Parrott, Roberta E., Roberts, Joseph L., Goldstein, David B., Buckley, Rebecca H., Zhong, Xiao-Ping
Publicado no Blood (2014)

Prioritizing Genetic Variants for Causality on the Basis of Preferential Linkage Disequilibrium

Por Zhu, Qianqian, Ge, Dongliang, Heinzen, Erin L., Dickson, Samuel P., Urban, Thomas J., Zhu, Mingfu, Maia, Jessica M., He, Min, Zhao, Qian, Shianna, Kevin V., Goldstein, David B.
Publicado em 2012

Functional Genetic Variation in the Basal Promoter of the Organic Cation/Carnitine Transporters OCTN1 (SLC22A4) and OCTN2 (SLC22A5)

Por Tahara, Harunobu, Yee, Sook Wah, Urban, Thomas J., Hesselson, Stephanie, Castro, Richard A., Kawamoto, Michiko, Stryke, Doug, Johns, Susan J., Ferrin, Thomas E., Kwok, Pui-Yan, Giacomini, Kathleen M.
Publicado em 2009

Population Pharmacokinetic Modeling of Plasma and Intracellular Ribavirin Concentrations in Patients with Chronic Hepatitis C Virus Infection

Por Wu, Liviawati S., Rower, Joseph E., Burton, James R., Anderson, Peter L., Hammond, Kyle P., Baouchi-Mokrane, Fafa, Everson, Gregory T., Urban, Thomas J., D'Argenio, David Z., Kiser, Jennifer J.
Publicado no Antimicrob Agents Chemother (2015)