Functional Genetic Variation in the Basal Promoter of the Organic Cation/Carnitine Transporters OCTN1 (SLC22A4) and OCTN2 (SLC22A5)

The organic cation/ergothioneine transporter OCTN1 (SLC22A4) and the high-affinity carnitine transporter OCTN2 (SLC22A5), play an important role in the disposition of xenobiotics and endogenous compounds. Here, we analyzed the sequence of the proximal promoter regions of OCTN1 and OCTN2 in four ethn...

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Détails bibliographiques
Auteurs principaux: Tahara, Harunobu, Yee, Sook Wah, Urban, Thomas J., Hesselson, Stephanie, Castro, Richard A., Kawamoto, Michiko, Stryke, Doug, Johns, Susan J., Ferrin, Thomas E., Kwok, Pui-Yan, Giacomini, Kathleen M.
Format: Artigo
Langue:Inglês
Publié: American Society for Pharmacology and Experimental Therapeutics 2009
Sujets:
Metabolism, Transport, and Pharmacogenomics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670604/
https://ncbi.nlm.nih.gov/pubmed/19141711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.146449
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