Genetic Variants in Multidrug and Toxic Compound Extrusion 1, hMATE1, Alter Transport Function

hMATE1 (human multidrug and toxin compound extrusion-1; encoded by SLC47A1) is thought to have an important function in the renal and hepatic elimination of drugs, endogenous compounds and environmental toxins. The goals of this study were to identify genetic variants of hMATE1 and to determine thei...

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Detalhes bibliográficos
Main Authors: Chen, Ying, Teranishi, Kristen, Li, Shuanglian, Yee, Sook Wah, Hesselson, Stephanie, Stryke, Doug, Johns, Susan J., Ferrin, Thomas E., Kwok, Pui, Giacomini, Kathleen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949062/
https://ncbi.nlm.nih.gov/pubmed/19172157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2008.19
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