Subcellular Localization of the HER4 Intracellular Domain, 4ICD, Identifies Distinct Prognostic Outcomes for Breast Cancer Patients

Por Thor, Ann D., Edgerton, Susan M., Jones, Frank E.
Publicado em 2009

Increased erbB3 promotes erbB2/neu-driven mammary tumor proliferation and co-targeting of erbB2/erbB3 receptors exhibits potent inhibitory effects on breast cancer cells

Por Lyu, Hui, Huang, Jingcao, Edgerton, Susan M, Thor, Ann D, He, Zhimin, Liu, Bolin
Publicado no Int J Clin Exp Pathol (2015)

The HER4/4ICD Estrogen Receptor Coactivator and BH3-Only Protein is an Effector of Tamoxifen-Induced Apoptosis

Por Naresh, Anjali, Thor, Ann D., Edgerton, Susan M., Torkko, Kathleen C., Kumar, Rakesh, Jones, Frank E.
Publicado em 2008

Metformin attenuates transforming growth factor beta (TGF-β) mediated oncogenesis in mesenchymal stem-like/claudin-low triple negative breast cancer

Por Wahdan-Alaswad, Reema, Harrell, J. Chuck, Fan, Zeying, Edgerton, Susan M., Liu, Bolin, Thor, Ann D.
Publicado no Cell Cycle (2016)

A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation

Por Kim, Moses M., Rivera, Melissa A., Botchkina, Inna L., Shalaby, Refaat, Thor, Ann D., Blackburn, Elizabeth H.
Publicado em 2001

The erbB3- and IGF-1 receptor-initiated signaling pathways exhibit distinct effects on lapatinib sensitivity against trastuzumab-resistant breast cancer cells

Por Lyu, Hui, Yang, Xiao He, Edgerton, Susan M., Thor, Ann D., Wu, Xiaoying, He, Zhimin, Liu, Bolin
Publicado no Oncotarget (2015)

Downregulation of miR-342 is associated with tamoxifen resistant breast tumors

Por Cittelly, Diana M, Das, Partha M, Spoelstra, Nicole S, Edgerton, Susan M, Richer, Jennifer K, Thor, Ann D, Jones, Frank E
Publicado em 2010

Metformin Selectively Targets Tumor-Initiating Cells in ErbB2-Overexpressing Breast Cancer Models

Por Zhu, Pei, Davis, Meghan, Blackwelder, Amanda J., Bachman, Nora, Liu, Bolin, Edgerton, Susan, Williams, Leonard L., Thor, Ann D., Yang, Xiaohe
Publicado no Cancer Prev Res (Phila) (2013)

Functional identification of distinct sets of antitumor activities mediated by the FKBP gene family

Por Fong, Sylvia, Mounkes, Leslie, Liu, Yong, Maibaum, Michael, Alonzo, Eric, Desprez, Pierre-Yves, Thor, Ann D., Kashani-Sabet, Mohammed, Debs, Robert J.
Publicado em 2003

Postpartum breast involution reveals regression of secretory lobules mediated by tissue-remodeling

Por Jindal, Sonali, Gao, Dexiang, Bell, Pat, Albrektsen, Grethe, Edgerton, Susan M, Ambrosone, Christine B, Thor, Ann D, Borges, Virginia F, Schedin, Pepper
Publicado em 2014

Metformin-Induced Killing of Triple-Negative Breast Cancer Cells Is Mediated by Reduction in Fatty Acid Synthase via miRNA-193b

Por Wahdan-Alaswad, Reema S., Cochrane, Dawn R., Spoelstra, Nicole S., Howe, Erin N., Edgerton, Susan M., Anderson, Steven M., Thor, Ann D., Richer, Jennifer K.
Publicado no Horm Cancer (2014)

Pilot trial of paclitaxel-trastuzumab adjuvant therapy for early stage breast cancer: a trial of the ECOG-ACRIN cancer research group (E2198)

Por Schneider, Bryan P, O'Neill, Anne, Shen, Fei, Sledge, George W, Thor, Ann D, Kahanic, Stephen P, Zander, Paul J, Davidson, Nancy E
Publicado no Br J Cancer (2015)

Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer

Por Giles, Erin D., Jindal, Sonali, Wellberg, Elizabeth A., Schedin, Troy, Anderson, Steven M., Thor, Ann D., Edwards, Dean P., MacLean, Paul S., Schedin, Pepper
Publicado no Breast Cancer Res (2018)

Functional interaction between mouse erbB3 and wild-type rat c-neu in transgenic mouse mammary tumor cells

Por Kim, Aeree, Liu, Bolin, Ordonez-Ercan, Dalia, Alvarez, Kathy M, Jones, Lynn D, McKimmey, Christine, Edgerton, Susan M, Yang, XiaoHe, Thor, Ann D
Publicado em 2005

Glucose promotes breast cancer aggression and reduces metformin efficacy

Por Wahdan-Alaswad, Reema, Fan, Zeying, Edgerton, Susan M, Liu, Bolin, Deng, Xin-Sheng, Arnadottir, Sigrid Salling, Richer, Jennifer K, Anderson, Steven M, Thor, Ann D
Publicado em 2013

Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer

Por Wang, Shuiliang, Huang, Jingcao, Lyu, Hui, Cai, Bo, Yang, Xiaoping, Li, Fang, Tan, Jianming, Edgerton, Susan M, Thor, Ann D, Lee, Choon-Kee, Liu, Bolin
Publicado em 2013

Obesity and overfeeding affecting both tumor and systemic metabolism activates the progesterone receptor to contribute to postmenopausal breast cancer

Por Giles, Erin D., Wellberg, Elizabeth A., Astling, David P., Anderson, Steven M., Thor, Ann D., Jindal, Sonali, Tan, Aik-Choon, Schedin, Pepper S., MacLean, Paul S.
Publicado em 2012

Identification of gene function and functional pathways by systemic plasmid-based ribozyme targeting in adult mice

Por Kashani-Sabet, Mohammed, Liu, Yong, Fong, Sylvia, Desprez, Pierre-Yves, Liu, Shuqing, Tu, Guanghuan, Nosrati, Mehdi, Handumrongkul, Chakkrapong, Liggitt, Denny, Thor, Ann D., Debs, Robert J.
Publicado em 2002

p53 Inactivation Upregulates p73 Expression through E2F-1 Mediated Transcription

Por Tophkhane, Chaitali, Yang, Shi-He, Jiang, Yunbo, Ma, Zhikun, Subramaniam, Dharmalingam, Anant, Shrikant, Yogosawa, Shingo, Sakai, Toshiyuki, Liu, Wan-Guo, Edgerton, Susan, Thor, Ann, Yang, Xiaohe
Publicado em 2012

Activation of cancerous inhibitor of PP2A (CIP2A) contributes to lapatinib resistance through induction of CIP2A-Akt feedback loop in ErbB2-positive breast cancer cells

Por Zhao, Ming, Howard, Erin W., Parris, Amanda B., Guo, Zhiying, Zhao, Qingxia, Ma, Zhikun, Xing, Ying, Liu, Bolin, Edgerton, Susan M., Thor, Ann D., Yang, Xiaohe
Publicado no Oncotarget (2017)