Metformin-Induced Killing of Triple-Negative Breast Cancer Cells Is Mediated by Reduction in Fatty Acid Synthase via miRNA-193b

The anti-diabetic drug metformin (1,1-dimethylbiguanide hydrochloride) reduces both the incidence and mortality of several types of cancer. Metformin has been shown to selectively kill cancer stem cells, and triple-negative breast cancer (TNBC) cell lines are more sensitive to the effects of metform...

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Detalhes bibliográficos
Publicado no:Horm Cancer
Main Authors: Wahdan-Alaswad, Reema S., Cochrane, Dawn R., Spoelstra, Nicole S., Howe, Erin N., Edgerton, Susan M., Anderson, Steven M., Thor, Ann D., Richer, Jennifer K.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570735/
https://ncbi.nlm.nih.gov/pubmed/25213330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12672-014-0188-8
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