Subcellular Localization of the HER4 Intracellular Domain, 4ICD, Identifies Distinct Prognostic Outcomes for Breast Cancer Patients

Por Thor, Ann D., Edgerton, Susan M., Jones, Frank E.
Publicado em 2009

Increased erbB3 promotes erbB2/neu-driven mammary tumor proliferation and co-targeting of erbB2/erbB3 receptors exhibits potent inhibitory effects on breast cancer cells

Por Lyu, Hui, Huang, Jingcao, Edgerton, Susan M, Thor, Ann D, He, Zhimin, Liu, Bolin
Publicado no Int J Clin Exp Pathol (2015)

The HER4/4ICD Estrogen Receptor Coactivator and BH3-Only Protein is an Effector of Tamoxifen-Induced Apoptosis

Por Naresh, Anjali, Thor, Ann D., Edgerton, Susan M., Torkko, Kathleen C., Kumar, Rakesh, Jones, Frank E.
Publicado em 2008

Metformin attenuates transforming growth factor beta (TGF-β) mediated oncogenesis in mesenchymal stem-like/claudin-low triple negative breast cancer

Por Wahdan-Alaswad, Reema, Harrell, J. Chuck, Fan, Zeying, Edgerton, Susan M., Liu, Bolin, Thor, Ann D.
Publicado no Cell Cycle (2016)

The erbB3- and IGF-1 receptor-initiated signaling pathways exhibit distinct effects on lapatinib sensitivity against trastuzumab-resistant breast cancer cells

Por Lyu, Hui, Yang, Xiao He, Edgerton, Susan M., Thor, Ann D., Wu, Xiaoying, He, Zhimin, Liu, Bolin
Publicado no Oncotarget (2015)

Downregulation of miR-342 is associated with tamoxifen resistant breast tumors

Por Cittelly, Diana M, Das, Partha M, Spoelstra, Nicole S, Edgerton, Susan M, Richer, Jennifer K, Thor, Ann D, Jones, Frank E
Publicado em 2010

Postpartum breast involution reveals regression of secretory lobules mediated by tissue-remodeling

Por Jindal, Sonali, Gao, Dexiang, Bell, Pat, Albrektsen, Grethe, Edgerton, Susan M, Ambrosone, Christine B, Thor, Ann D, Borges, Virginia F, Schedin, Pepper
Publicado em 2014

Metformin-Induced Killing of Triple-Negative Breast Cancer Cells Is Mediated by Reduction in Fatty Acid Synthase via miRNA-193b

Por Wahdan-Alaswad, Reema S., Cochrane, Dawn R., Spoelstra, Nicole S., Howe, Erin N., Edgerton, Susan M., Anderson, Steven M., Thor, Ann D., Richer, Jennifer K.
Publicado no Horm Cancer (2014)

Functional interaction between mouse erbB3 and wild-type rat c-neu in transgenic mouse mammary tumor cells

Por Kim, Aeree, Liu, Bolin, Ordonez-Ercan, Dalia, Alvarez, Kathy M, Jones, Lynn D, McKimmey, Christine, Edgerton, Susan M, Yang, XiaoHe, Thor, Ann D
Publicado em 2005

Glucose promotes breast cancer aggression and reduces metformin efficacy

Por Wahdan-Alaswad, Reema, Fan, Zeying, Edgerton, Susan M, Liu, Bolin, Deng, Xin-Sheng, Arnadottir, Sigrid Salling, Richer, Jennifer K, Anderson, Steven M, Thor, Ann D
Publicado em 2013

Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer

Por Wang, Shuiliang, Huang, Jingcao, Lyu, Hui, Cai, Bo, Yang, Xiaoping, Li, Fang, Tan, Jianming, Edgerton, Susan M, Thor, Ann D, Lee, Choon-Kee, Liu, Bolin
Publicado em 2013

Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures

Por Kabos, Peter, Finlay-Schultz, Jessica, Li, Chunling, Kline, Enos, Finlayson, Christina, Wisell, Joshua, Manuel, Christopher A., Edgerton, Susan M., Harrell, J. Chuck, Elias, Anthony, Sartorius, Carol A.
Publicado em 2012

Genome-wide functional genetic screen with the anticancer agent AMPI-109 identifies PRL-3 as an oncogenic driver in triple-negative breast cancers

Por Gari, Hamid H., Gearheart, Christy M., Fosmire, Susan, DeGala, Gregory D., Fan, Zeying, Torkko, Kathleen C., Edgerton, Susan M., Lucia, M. Scott, Ray, Rahul, Thor, Ann D., Porter, Christopher C., Lambert, James R.
Publicado no Oncotarget (2016)

Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide

Por Cochrane, Dawn R, Bernales, Sebastián, Jacobsen, Britta M, Cittelly, Diana M, Howe, Erin N, D’Amato, Nicholas C, Spoelstra, Nicole S, Edgerton, Susan M, Jean, Annie, Guerrero, Javier, Gómez, Francisco, Medicherla, Satyanarayana, Alfaro, Iván E, McCullagh, Emma, Jedlicka, Paul, Torkko, Kathleen C, Thor, Ann D, Elias, Anthony D, Protter, Andrew A, Richer, Jennifer K
Publicado em 2014