IRE1-Independent Gain Control of the Unfolded Protein Response

Por Leber, Jess H, Bernales, Sebastián, Walter, Peter
Publicado em 2004

Autophagy Counterbalances Endoplasmic Reticulum Expansion during the Unfolded Protein Response

Por Bernales, Sebastián, McDonald, Kent L, Walter, Peter
Publicado em 2006

Unfolded protein stress in the endoplasmic reticulum and mitochondria: a role in neurodegeneration

Por Bernales, Sebastián, Soto, Marisol Morales, McCullagh, Emma
Publicado em 2012

Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic

Por Mendez, Aaron S, Alfaro, Jennifer, Morales-Soto, Marisol A, Dar, Arvin C, McCullagh, Emma, Gotthardt, Katja, Li, Han, Acosta-Alvear, Diego, Sidrauski, Carmela, Korennykh, Alexei V, Bernales, Sebastian, Shokat, Kevan M, Walter, Peter
Publicado no eLife (2015)

Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain

Por Steele, John W., Ju, Shulin, Lachenmayer, M. Lenard, Liken, Jessica, Stock, Aryeh, Kim, Soong Ho, Delgado, Luz M., Alfaro, Iván E, Bernales, Sebastian, Verdile, Giuseppe, Bharadwaj, Prashant, Gupta, Veer, Barr, Renae, Friss, Amy, Dolios, Georgia, Wang, Rong, Ringe, Dagmar, Protter, Andrew A., Martins, Ralph N., Ehrlich, Michelle E., Yue, Zhenyu, Petsko, Gregory A., Gandy, Sam
Publicado em 2012

Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide

Por Cochrane, Dawn R, Bernales, Sebastián, Jacobsen, Britta M, Cittelly, Diana M, Howe, Erin N, D’Amato, Nicholas C, Spoelstra, Nicole S, Edgerton, Susan M, Jean, Annie, Guerrero, Javier, Gómez, Francisco, Medicherla, Satyanarayana, Alfaro, Iván E, McCullagh, Emma, Jedlicka, Paul, Torkko, Kathleen C, Thor, Ann D, Elias, Anthony D, Protter, Andrew A, Richer, Jennifer K
Publicado em 2014

Discovery of Pyrazolopyrimidine Derivatives as Novel Dual Inhibitors of BTK and PI3Kδ

Por Pujala, Brahmam, Agarwal, Anil K., Middya, Sandip, Banerjee, Monali, Surya, Arjun, Nayak, Anjan K., Gupta, Ashu, Khare, Sweta, Guguloth, Rambabu, Randive, Nitin A., Shinde, Bharat U., Thakur, Anamika, Patel, Dhananjay I., Raja, Mohd., Green, Michael J., Alfaro, Jennifer, Avila, Patricio, Pérez de Arce, Felipe, Almirez, Ramona G., Kanno, Stacy, Bernales, Sebastián, Hung, David T., Chakravarty, Sarvajit, McCullagh, Emma, Quinn, Kevin P., Rai, Roopa, Pham, Son M.
Publicado no ACS Med Chem Lett (2016)

Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer’s mouse model

Por Steele, John W., Lachenmayer, M. Lenard, Ju, Shulin, Stock, Aryeh, Liken, Jessica, Kim, Soong Ho, Delgado, Luz M., Alfaro, Iván E, Bernales, Sebastian, Verdile, Giuseppe, Bharadwaj, Prashant, Gupta, Veer, Barr, Renae, Friss, Amy, Dolios, Georgia, Wang, Rong, Ringe, Dagmar, Fraser, Paul, Westaway, David, St George-Hyslop, Peter H., Szabo, Paul, Relkin, Norman R., Buxbaum, Joseph D., Glabe, Charles G., Protter, Andrew A., Martins, Ralph N., Ehrlich, Michelle E., Petsko, Gregory A., Yue, Zhenyu, Gandy, Sam
Publicado em 2012