Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures

Bypassing estrogen receptor (ER) signaling during development of endocrine resistance remains the most common cause of disease progression and mortality in breast cancer patients. To date, the majority of molecular research on ER action in breast cancer has occurred in cell line models derived from...

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Main Authors: Kabos, Peter, Finlay-Schultz, Jessica, Li, Chunling, Kline, Enos, Finlayson, Christina, Wisell, Joshua, Manuel, Christopher A., Edgerton, Susan M., Harrell, J. Chuck, Elias, Anthony, Sartorius, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818141/
https://ncbi.nlm.nih.gov/pubmed/22821401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2164-8
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