Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures

Bypassing estrogen receptor (ER) signaling during development of endocrine resistance remains the most common cause of disease progression and mortality in breast cancer patients. To date, the majority of molecular research on ER action in breast cancer has occurred in cell line models derived from...

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Main Authors: Kabos, Peter, Finlay-Schultz, Jessica, Li, Chunling, Kline, Enos, Finlayson, Christina, Wisell, Joshua, Manuel, Christopher A., Edgerton, Susan M., Harrell, J. Chuck, Elias, Anthony, Sartorius, Carol A.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818141/
https://ncbi.nlm.nih.gov/pubmed/22821401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2164-8
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