Glucose promotes breast cancer aggression and reduces metformin efficacy

Metformin treatment has been associated with a decrease in breast cancer risk and improved survival. Metformin induces complex cellular changes, resulting in decreased tumor cell proliferation, reduction of stem cells, and apoptosis. Using a carcinogen-induced rodent model of mammary tumorigenesis,...

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Autores principales: Wahdan-Alaswad, Reema, Fan, Zeying, Edgerton, Susan M, Liu, Bolin, Deng, Xin-Sheng, Arnadottir, Sigrid Salling, Richer, Jennifer K, Anderson, Steven M, Thor, Ann D
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905068/
https://ncbi.nlm.nih.gov/pubmed/24107633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26641
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