Metformin Selectively Targets Tumor-Initiating Cells in ErbB2-Overexpressing Breast Cancer Models

Metformin is an oral biguanide used for type II diabetes. Epidemiologic studies suggest a link between metformin use and reduced risk of breast and other types of cancers. ErbB2-expressing breast cancer is a subgroup of tumors with poor prognosis. Previous studies demonstrated that metformin is a po...

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Publicado no:Cancer Prev Res (Phila)
Main Authors: Zhu, Pei, Davis, Meghan, Blackwelder, Amanda J., Bachman, Nora, Liu, Bolin, Edgerton, Susan, Williams, Leonard L., Thor, Ann D., Yang, Xiaohe
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497590/
https://ncbi.nlm.nih.gov/pubmed/24322659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0181
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