p53 Inactivation Upregulates p73 Expression through E2F-1 Mediated Transcription

While p73 overexpression has been associated with increased apoptosis in cancer tissues, p73 overexpressing tumors appear to be of high grade malignancy. Why this putative tumor suppressor is overexpressed in cancer cells and what the function of overexpressed p73 is in breast cancers are critical q...

Full description

Saved in:
Bibliographic Details
Main Authors: Tophkhane, Chaitali, Yang, Shi-He, Jiang, Yunbo, Ma, Zhikun, Subramaniam, Dharmalingam, Anant, Shrikant, Yogosawa, Shingo, Sakai, Toshiyuki, Liu, Wan-Guo, Edgerton, Susan, Thor, Ann, Yang, Xiaohe
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431388/
https://ncbi.nlm.nih.gov/pubmed/22952705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043564
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items