IRAP Inhibitors: M1-Aminopeptidase Family Inspiration

von Barlow, Nicholas, Thompson, Philip E.
Veröffentlicht in Front Pharmacol (2020)

Structural Determinants of Isoform Selectivity in PI3K Inhibitors

von Miller, Michelle S., Thompson, Philip E., Gabelli, Sandra B.
Veröffentlicht in Biomolecules (2019)

Structure—Activity Relationships of Polymyxin Antibiotics

von Velkov, Tony, Thompson, Philip E., Nation, Roger L., Li, Jian
Veröffentlicht 2010

Pharmacology of polymyxins: new insights into an ‘old’ class of antibiotics

von Velkov, Tony, Roberts, Kade D, Nation, Roger L, Thompson, Philip E, Li, Jian
Veröffentlicht 2013

Structure-Activity Relationship Exploration of Kv1.3 Blockers Based on Diphenoxylate

von Nguyen, William, Howard, Brittany L., Jenkins, David P., Wulff, Heike, Thompson, Philip E., Manallack, David T.
Veröffentlicht 2012

Teaching ‘Old’ Polymyxins New Tricks: New-Generation Lipopeptides Targeting Gram-Negative ‘Superbugs’

von Velkov, Tony, Roberts, Kade D., Nation, Roger L., Wang, Jiping, Thompson, Philip E., Li, Jian
Veröffentlicht 2014

Design and Evaluation of Novel Polymyxin Fluorescent Probes

von Yun, Bo, Roberts, Kade D., Thompson, Philip E., Nation, Roger L., Velkov, Tony, Li, Jian
Veröffentlicht in Sensors (Basel) (2017)

l-Aminoacyl-triazine Derivatives Are Isoform-Selective PI3Kβ Inhibitors That Target Nonconserved Asp862 of PI3Kβ

von Pinson, Jo-Anne, Zheng, Zhaohua, Miller, Michelle S., Chalmers, David K., Jennings, Ian G., Thompson, Philip E.
Veröffentlicht 2012

Class II but Not Second Class—Prospects for the Development of Class II PI3K Inhibitors

von Mountford, Simon J., Zheng, Zhaohua, Sundaram, Krithika, Jennings, Ian G., Hamilton, Justin R., Thompson, Philip E.
Veröffentlicht in ACS Med Chem Lett (2014)

Use of Kv1.3 Blockers for Inflammatory Skin Conditions

von Nguyen, William, Howard, Brittany L., Neale, Diana S., Thompson, Philip E., White, Paul J., Wulff, Heike, Manallack, David T.
Veröffentlicht 2010

Polymyxins and analogs bind to ribosomal RNA and interfere with eukaryotic translation in vitro

von McCoy, Lisa S., Roberts, Kade D., Nation, Roger L., Thompson, Philip E., Velkov, Tony, Li, Jian, Tor, Yitzhak
Veröffentlicht 2013

The Phytosulfokine (PSK) Receptor Is Capable of Guanylate Cyclase Activity and Enabling Cyclic GMP-dependent Signaling in Plants

von Kwezi, Lusisizwe, Ruzvidzo, Oziniel, Wheeler, Janet I., Govender, Kershini, Iacuone, Sylvana, Thompson, Philip E., Gehring, Chris, Irving, Helen R.
Veröffentlicht 2011

Measuring Polymyxin Uptake by Renal Tubular Cells: Is BODIPY-Polymyxin B an Appropriate Probe?

von Azad, Mohammad A. K., Yun, Bo, Roberts, Kade D., Nation, Roger L., Thompson, Philip E., Velkov, Tony, Li, Jian
Veröffentlicht 2014

Identification of a unique filamin A binding region within the cytoplasmic domain of glycoprotein Ibα

von Cranmer, Susan L., Pikovski, Inna, Mangin, Pierre, Thompson, Philip E., Domagala, Teresa, Frazzetto, Mark, Salem, Hatem H., Jackson, Shaun P.
Veröffentlicht 2005

Development of cognitive enhancers based on inhibition of insulin-regulated aminopeptidase

von Chai, Siew Yeen, Yeatman, Holly R, Parker, Michael W, Ascher, David B, Thompson, Philip E, Mulvey, Hayley T, Albiston, Anthony L
Veröffentlicht 2008

A secondary mode of action of polymyxins against Gram-negative bacteria involves the inhibition of NADH-quinone oxidoreductase activity

von Deris, Zakuan Z., Akter, Jesmin, Sivanesan, Sivashangarie, Roberts, Kade D., Thompson, Philip E., Nation, Roger L., Li, Jian, Velkov, Tony
Veröffentlicht 2013

Design, synthesis and evaluation of a new fluorescent probe for measuring polymyxin-lipopolysaccharide binding interactions

von Soon, Rachel L., Velkov, Tony, Chiu, Francis, Thompson, Philip E., Kancharla, Rashmi, Roberts, Kade, Larson, Ian, Nation, Roger L., Li, Jian
Veröffentlicht 2010

Imaging the distribution of polymyxins in the kidney

von Yun, Bo, Azad, Mohammad A. K., Wang, Jiping, Nation, Roger L., Thompson, Philip E., Roberts, Kade D., Velkov, Tony, Li, Jian
Veröffentlicht in J Antimicrob Chemother (2015)

Antimicrobial Activity and Toxicity of the Major Lipopeptide Components of Polymyxin B and Colistin: Last-line Antibiotics against Multidrug-Resistant Gram-negative Bacteria

von Roberts, Kade D., Azad, Mohammad A. K., Wang, Jiping, Horne, Andrew S, Thompson, Philip E., Nation, Roger L., Velkov, Tony, Li, Jian
Veröffentlicht in ACS Infect Dis (2015)

Thiazolidinedione-Based PI3Kα Inhibitors: An Analysis of Biochemical and Virtual Screening Methods

von Pinson, Jo-Anne, Schmidt-Kittler, Oleg, Zhu, Jiuxiang, Jennings, Ian G, Kinzler, Kenneth W, Vogelstein, Bert, Chalmers, David K, Thompson, Philip E
Veröffentlicht 2011