Imaging the distribution of polymyxins in the kidney

OBJECTIVES: Dose-limiting nephrotoxicity remains the Achilles' heel of polymyxin B and polymyxin E (also known as colistin), which are important last-line antibiotics used against infections caused by MDR Gram-negative ‘superbugs’. An understanding of the mechanisms of nephrotoxicity, including...

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Dades bibliogràfiques
Publicat a:J Antimicrob Chemother
Autors principals: Yun, Bo, Azad, Mohammad A. K., Wang, Jiping, Nation, Roger L., Thompson, Philip E., Roberts, Kade D., Velkov, Tony, Li, Jian
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319485/
https://ncbi.nlm.nih.gov/pubmed/25377569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku441
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