Development of cognitive enhancers based on inhibition of insulin-regulated aminopeptidase

The peptides angiotensin IV and LVV-hemorphin 7 were found to enhance memory in a number of memory tasks and reverse the performance deficits in animals with experimentally induced memory loss. These peptides bound specifically to the enzyme insulin-regulated aminopeptidase (IRAP), which is proposed...

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Detalhes bibliográficos
Main Authors: Chai, Siew Yeen, Yeatman, Holly R, Parker, Michael W, Ascher, David B, Thompson, Philip E, Mulvey, Hayley T, Albiston, Anthony L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604898/
https://ncbi.nlm.nih.gov/pubmed/19090987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-9-S2-S14
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