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Structural Basis of Inhibition of Human Insulin-Regulated Aminopeptidase (IRAP) by Aryl Sulfonamides
[Image: see text] The insulin-regulated aminopeptidase (IRAP) is a membrane-bound zinc metallopeptidase with many important regulatory functions. It has been demonstrated that inhibition of IRAP by angiotensin IV (Ang IV) and other peptides, as well as more druglike inhibitors, improves cognition in...
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| Vydáno v: | ACS Omega |
|---|---|
| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Chemical Society
2018
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6045421/ https://ncbi.nlm.nih.gov/pubmed/30023895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b00595 |
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