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Structural Basis of Inhibition of Human Insulin-Regulated Aminopeptidase (IRAP) by Aryl Sulfonamides
[Image: see text] The insulin-regulated aminopeptidase (IRAP) is a membrane-bound zinc metallopeptidase with many important regulatory functions. It has been demonstrated that inhibition of IRAP by angiotensin IV (Ang IV) and other peptides, as well as more druglike inhibitors, improves cognition in...
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| Gepubliceerd in: | ACS Omega |
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| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Chemical Society
2018
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| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6045421/ https://ncbi.nlm.nih.gov/pubmed/30023895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b00595 |
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