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Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Arylsulfonamides
The inhibition of insulin-regulated aminopeptidase (IRAP, EC 3.4.11.3) by angiotenesin IV is known to improve memory and learning in rats. Screening 10 500 low-molecular-weight compounds in an enzyme inhibition assay with IRAP from Chinese Hamster Ovary (CHO) cells provided an arylsulfonamide (N-(3-...
שמור ב:
| הוצא לאור ב: | ChemistryOpen |
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| Main Authors: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Blackwell Publishing Ltd
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4280825/ https://ncbi.nlm.nih.gov/pubmed/25558444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201402027 |
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