Combined inhibition of CDK and HDAC as a promising therapeutic strategy for both cutaneous and uveal metastatic melanoma

Por Heijkants, Renier, Willekens, Karen, Schoonderwoerd, Mark, Teunisse, Amina, Nieveen, Maaike, Radaelli, Enrico, Hawinkels, Luuk, Marine, Jean-Christophe, Jochemsen, Aart
Publicado no Oncotarget (2017)

Differential Roles of ATM- and Chk2-Mediated Phosphorylations of Hdmx in Response to DNA Damage

Por Pereg, Yaron, Lam, Suzanne, Teunisse, Amina, Biton, Sharon, Meulmeester, Erik, Mittelman, Leonid, Buscemi, Giacomo, Okamoto, Koji, Taya, Yoichi, Shiloh, Yosef, Jochemsen, Aart G.
Publicado em 2006

High levels of Hdmx promote cell growth in a subset of uveal melanomas

Por de Lange, Job, Teunisse, Amina FAS, Vries, Matty Verlaan-de, Lodder, Kirsten, Lam, Suzanne, Luyten, Gregorius PM, Bernal, Federico, Jager, Martine J, Jochemsen, Aart G
Publicado em 2012

Oncogenic functions of hMDMX in in vitro transformation of primary human fibroblasts and embryonic retinoblasts

Por Lenos, Kristiaan, de Lange, Job, Teunisse, Amina FAS, Lodder, Kirsten, Verlaan-de Vries, Matty, Wiercinska, Eliza, van der Burg, Marja JM, Szuhai, Karoly, Jochemsen, Aart G
Publicado em 2011

Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage

Por Pereg, Yaron, Shkedy, Dganit, de Graaf, Petra, Meulmeester, Erik, Edelson-Averbukh, Marina, Salek, Mogjiborahman, Biton, Sharon, Teunisse, Amina F. A. S., Lehmann, Wolf D., Jochemsen, Aart G., Shiloh, Yosef
Publicado em 2005

Analysis of CRISPR‐Cas9 screens identifies genetic dependencies in melanoma

Por Christodoulou, Eirini, Rashid, Mamunur, Pacini, Clare, Droop, Alastair, Robertson, Holly, van Groningen, Tim, Teunisse, Amina F. A. S., Iorio, Francesco, Jochemsen, Aart G., Adams, David J., van Doorn, Remco
Publicado no Pigment Cell Melanoma Res (2020)

DNA Damage-Induced Phosphorylation of MdmX at Serine 367 Activates p53 by Targeting MdmX for Mdm2-Dependent Degradation

Por Okamoto, Koji, Kashima, Kenji, Pereg, Yaron, Ishida, Michiko, Yamazaki, Satomi, Nota, Ayumi, Teunisse, Amina, Migliorini, Domenico, Kitabayashi, Issay, Marine, Jean-Christophe, Prives, Carol, Shiloh, Yosef, Jochemsen, Aart G., Taya, Yoichi
Publicado em 2005

HDMX-L Is Expressed from a Functional p53-responsive Promoter in the First Intron of the HDMX Gene and Participates in an Autoregulatory Feedback Loop to Control p53 Activity

Por Phillips, Anna, Teunisse, Amina, Lam, Suzanne, Lodder, Kirsten, Darley, Matthew, Emaduddin, Muhammad, Wolf, Anja, Richter, Julia, de Lange, Job, Verlaan-de Vries, Matty, Lenos, Kristiaan, Böhnke, Anja, Bartel, Frank, Blaydes, Jeremy P., Jochemsen, Aart G.
Publicado em 2010

Overexpression of EZH2 in conjunctival melanoma offers a new therapeutic target

Por Cao, Jinfeng, Pontes, Kelly CS, Heijkants, Renier C, Brouwer, Niels J, Groenewoud, Arwin, Jordanova, Ekaterina S, Marinkovic, Marina, van Duinen, Sjoerd, Teunisse, Amina FAS, Verdijk, Robert M, Snaar‐Jagalska, Ewa, Jochemsen, Aart G, Jager, Martine J
Publicado no J Pathol (2018)

Differential Expression of DNA Repair Genes in Prognostically-Favorable versus Unfavorable Uveal Melanoma

Por Dogrusöz, Mehmet, Ruschel Trasel, Andrea, Cao, Jinfeng, Ҫolak, Selҫuk, van Pelt, Sake I., Kroes, Wilma G. M., Teunisse, Amina F. A. S., Alsafadi, Samar, van Duinen, Sjoerd G., Luyten, Gregorius P. M., van der Velden, Pieter A., Amaro, Adriana, Pfeffer, Ulrich, Jochemsen, Aart G., Jager, Martine J.
Publicado no Cancers (Basel) (2019)

Lack of myeloid cell infiltration as an acquired resistance strategy to immunotherapy

Por Beyranvand Nejad, Elham, Labrie, Camilla, Abdulrahman, Ziena, van Elsas, Marit J, Rademaker, Eva, Kleinovink, Jan Willem, van der Sluis, Tetje C, van Duikeren, Suzanne, Teunisse, Amina F A.S, Jochemsen, Aart G, Oosting, Jan, de Miranda, Noel F C C, Van Hall, Thorbald, Arens, Ramon, van der Burg, Sjoerd H
Publicado no J Immunother Cancer (2020)