Combined inhibition of CDK and HDAC as a promising therapeutic strategy for both cutaneous and uveal metastatic melanoma

Very little to no improvement in overall survival has been seen in patients with advanced non-resectable cutaneous melanoma or metastatic uveal melanoma in decades, highlighting the need for novel therapeutic options. In this study we investigated as a potential novel therapeutic intervention for bo...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Heijkants, Renier, Willekens, Karen, Schoonderwoerd, Mark, Teunisse, Amina, Nieveen, Maaike, Radaelli, Enrico, Hawinkels, Luuk, Marine, Jean-Christophe, Jochemsen, Aart
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814203/
https://ncbi.nlm.nih.gov/pubmed/29464063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23485
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