Analysis of CRISPR‐Cas9 screens identifies genetic dependencies in melanoma

Targeting the MAPK signaling pathway has transformed the treatment of metastatic melanoma. CRISPR‐Cas9 genetic screens provide a genome‐wide approach to uncover novel genetic dependencies that might serve as therapeutic targets. Here, we analyzed recently reported CRISPR‐Cas9 screens comparing data...

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Bibliographic Details
Published in:Pigment Cell Melanoma Res
Main Authors: Christodoulou, Eirini, Rashid, Mamunur, Pacini, Clare, Droop, Alastair, Robertson, Holly, van Groningen, Tim, Teunisse, Amina F. A. S., Iorio, Francesco, Jochemsen, Aart G., Adams, David J., van Doorn, Remco
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7818247/
https://ncbi.nlm.nih.gov/pubmed/32767816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12919
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