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The effect of bacterial mutation rate on the evolution of CRISPR-Cas adaptive immunity

CRISPR-Cas immune systems are present in around half of bacterial genomes. Given the specificity and adaptability of this immune mechanism, it is perhaps surprising that they are not more widespread. Recent insights into the requirement for specific host factors for the function of some CRISPR-Cas s...

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Dades bibliogràfiques
Publicat a:Philos Trans R Soc Lond B Biol Sci
Autors principals: Chevallereau, Anne, Meaden, Sean, van Houte, Stineke, Westra, Edze R., Rollie, Clare
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452272/
https://ncbi.nlm.nih.gov/pubmed/30905293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2018.0094
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