Anti-CRISPR Phages Cooperate to Overcome CRISPR-Cas Immunity

Some phages encode anti-CRISPR (acr) genes, which antagonize bacterial CRISPR-Cas immune systems by binding components of its machinery, but it is less clear how deployment of these acr genes impacts phage replication and epidemiology. Here, we demonstrate that bacteria with CRISPR-Cas resistance ar...

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Publicado en:Cell
Main Authors: Landsberger, Mariann, Gandon, Sylvain, Meaden, Sean, Rollie, Clare, Chevallereau, Anne, Chabas, Hélène, Buckling, Angus, Westra, Edze R., van Houte, Stineke
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086933/
https://ncbi.nlm.nih.gov/pubmed/30033365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.05.058
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