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Anti-CRISPR Phages Cooperate to Overcome CRISPR-Cas Immunity

Some phages encode anti-CRISPR (acr) genes, which antagonize bacterial CRISPR-Cas immune systems by binding components of its machinery, but it is less clear how deployment of these acr genes impacts phage replication and epidemiology. Here, we demonstrate that bacteria with CRISPR-Cas resistance ar...

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Bibliografiske detaljer
Udgivet i:Cell
Main Authors: Landsberger, Mariann, Gandon, Sylvain, Meaden, Sean, Rollie, Clare, Chevallereau, Anne, Chabas, Hélène, Buckling, Angus, Westra, Edze R., van Houte, Stineke
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086933/
https://ncbi.nlm.nih.gov/pubmed/30033365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.05.058
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