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The effect of bacterial mutation rate on the evolution of CRISPR-Cas adaptive immunity

CRISPR-Cas immune systems are present in around half of bacterial genomes. Given the specificity and adaptability of this immune mechanism, it is perhaps surprising that they are not more widespread. Recent insights into the requirement for specific host factors for the function of some CRISPR-Cas s...

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Detalles Bibliográficos
Publicado en:Philos Trans R Soc Lond B Biol Sci
Autores principales: Chevallereau, Anne, Meaden, Sean, van Houte, Stineke, Westra, Edze R., Rollie, Clare
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452272/
https://ncbi.nlm.nih.gov/pubmed/30905293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2018.0094
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