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CRISPR-Cas immunity leads to a coevolutionary arms race between Streptococcus thermophilus and lytic phage

CRISPR-Cas is an adaptive prokaryotic immune system that prevents phage infection. By incorporating phage-derived ‘spacer’ sequences into CRISPR loci on the host genome, future infections from the same phage genotype can be recognized and the phage genome cleaved. However, the phage can escape CRISP...

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書目詳細資料
發表在:Philos Trans R Soc Lond B Biol Sci
Main Authors: Common, Jack, Morley, Daniel, Westra, Edze R., van Houte, Stineke
格式: Artigo
語言:Inglês
出版: The Royal Society 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452269/
https://ncbi.nlm.nih.gov/pubmed/30905285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2018.0098
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