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CRISPR-Cas immunity leads to a coevolutionary arms race between Streptococcus thermophilus and lytic phage
CRISPR-Cas is an adaptive prokaryotic immune system that prevents phage infection. By incorporating phage-derived ‘spacer’ sequences into CRISPR loci on the host genome, future infections from the same phage genotype can be recognized and the phage genome cleaved. However, the phage can escape CRISP...
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| Publicado no: | Philos Trans R Soc Lond B Biol Sci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6452269/ https://ncbi.nlm.nih.gov/pubmed/30905285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2018.0098 |
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