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CRISPR-Cas immunity leads to a coevolutionary arms race between Streptococcus thermophilus and lytic phage

CRISPR-Cas is an adaptive prokaryotic immune system that prevents phage infection. By incorporating phage-derived ‘spacer’ sequences into CRISPR loci on the host genome, future infections from the same phage genotype can be recognized and the phage genome cleaved. However, the phage can escape CRISP...

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Dades bibliogràfiques
Publicat a:Philos Trans R Soc Lond B Biol Sci
Autors principals: Common, Jack, Morley, Daniel, Westra, Edze R., van Houte, Stineke
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452269/
https://ncbi.nlm.nih.gov/pubmed/30905285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2018.0098
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