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CRISPR-Cas immunity leads to a coevolutionary arms race between Streptococcus thermophilus and lytic phage

CRISPR-Cas is an adaptive prokaryotic immune system that prevents phage infection. By incorporating phage-derived ‘spacer’ sequences into CRISPR loci on the host genome, future infections from the same phage genotype can be recognized and the phage genome cleaved. However, the phage can escape CRISP...

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Detaylı Bibliyografya
Yayımlandı:Philos Trans R Soc Lond B Biol Sci
Asıl Yazarlar: Common, Jack, Morley, Daniel, Westra, Edze R., van Houte, Stineke
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Royal Society 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452269/
https://ncbi.nlm.nih.gov/pubmed/30905285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2018.0098
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